This thesis describes the epidemiology of Streptococcus pneumoniae (pneumococci) and
other respiratory pathogens after introduction of the 13-valent pneumococcal conjugate …

Objectives To determine the antibiotic susceptibility and serotype distribution of colonizing
Streptococcus pneumoniae in Tanzanian children. Serial cross-sectional surveys were …

Introduction Pneumococcal conjugate vaccines have reduced severe disease attributed to
vaccine-type pneumococci in children. However, the effect is dependent on serotype …

Background The study objective was to determine the carriage and serotype distribution of
Streptococcus pneumoniae among children in Accra, Ghana, five years after the introduction …

Background Streptococcus pneumoniae remains a major contributor to childhood infections
and deaths globally. In Cameroon, the 13-valent pneumococcal conjugate vaccine (PCV13) …

Children in Angola are affected by a high burden of disease caused by pneumococcal
infections. The 13-valent pneumococcal conjugate vaccine (PCV13) was introduced in the …

Background Pneumonia is the major cause of death in children globally, with more than
900,000 deaths annually in children under five years of age. Streptococcus pneumoniae …

Background Pneumococci are spread by persons with nasopharyngeal colonization, a
necessary precursor to invasive disease. Pneumococcal conjugate vaccines can prevent …

Background Pneumococcal vaccine immunizations may be responsible for alterations in
serotype epidemiology within a region. This study investigated the pneumococcal carriage …

Background Pneumococcal conjugate vaccines have been introduced in the infant
immunisation programmes in many countries to reduce the rate of fatal pneumococcal …