[HTML][HTML] Chitosan-based hemostatic hydrogels: The concept, mechanism, application, and prospects

P Fan, Y Zeng, D Zaldivar-Silva, L Agüero, S Wang - Molecules, 2023 - mdpi.com
The design of new hemostatic materials to mitigate uncontrolled bleeding in emergencies is
challenging. Chitosan-based hemostatic hydrogels have frequently been used for …

Recent advances of chitosan as a hemostatic material: Hemostatic mechanism, material design and prospective application

S Zhang, X Lei, Y Lv, L Wang, LN Wang - Carbohydrate Polymers, 2023 - Elsevier
Uncontrolled hemorrhage arising from surgery or trauma may cause morbidity and even
mortality. Therefore, facilitating control of severe bleeding is imperative for health care …

[HTML][HTML] Chitosan-based composite materials for prospective hemostatic applications

Z Hu, DY Zhang, ST Lu, PW Li, SD Li - Marine drugs, 2018 - mdpi.com
Effective hemostasis is vital to reduce the pain and mortality of patients, and the research
and development of hemostatic materials are prerequisite for effective hemostasis. Chitosan …

[HTML][HTML] Chitosan-Based Biomaterials for Hemostatic Applications: A Review of Recent Advances

D Gheorghiță, H Moldovan, A Robu, AI Bița… - International journal of …, 2023 - mdpi.com
Hemorrhage is a detrimental event present in traumatic injury, surgery, and disorders of
bleeding that can become life-threatening if not properly managed. Moreover, uncontrolled …

Chitosan-based hemostatic sponges as new generation hemostatic materials for uncontrolled bleeding emergency: Modification, composition, and applications

Z Liu, Y Xu, H Su, X Jing, D Wang, S Li, Y Chen… - Carbohydrate …, 2023 - Elsevier
The choice of hemostatic technique is a curial concern for surgery and as first-aid treatment
in combat. To treat uncontrolled bleeding in complex wound environments, chitosan-based …

Chitosan-based multifunctional flexible hemostatic bio-hydrogel

F Song, Y Kong, C Shao, Y Cheng, J Lu, Y Tao, J Du… - Acta biomaterialia, 2021 - Elsevier
Realizing the potential application of chitosan as an effective biomedical hemostatic agent
has become an emerging research hotspot. However, fabricating a flexible chitosan-based …

Synthetic poly (vinyl alcohol)–chitosan as a new type of highly efficient hemostatic sponge with blood-triggered swelling and high biocompatibility

YF Zhao, JY Zhao, WZ Hu, K Ma, Y Chao… - Journal of Materials …, 2019 - pubs.rsc.org
Rapid and effective hemostasis for a noncompressible hemorrhage is the key to control
bleeding and reduce mortality. Chitosan (CS) has been widely used as a popular hemostatic …

Vasoconstrictor and coagulation activator entrapped chitosan based composite hydrogel for rapid bleeding control

MN Sundaram, U Mony, PK Varma… - Carbohydrate Polymers, 2021 - Elsevier
Chitosan (Cs) as a hemostatic agent has been in use to control hemorrage. Composite
hydrogel formed by entrapment of vasoconstrictor-potassium aluminium sulfate (0.25% PA) …

New injectable chitosan-hyaluronic acid based hydrogels for hemostasis and wound healing

H Weng, W Jia, M Li, Z Chen - Carbohydrate polymers, 2022 - Elsevier
It is a challenge to develop hemostatic and wound dressings that are used for irregular
shape and deep wound. Herein, a series of novel N-succinyl chitosan-oxidized hyaluronic …

Thermoresponsive chitosan/DOPA-based hydrogel as an injectable therapy approach for tissue-adhesion and hemostasis

Y Shou, J Zhang, S Yan, P Xia, P Xu, G Li… - ACS biomaterials …, 2020 - ACS Publications
Chitosan (CS) hydrogels are widely used in wound hemostatic agents due to their superior
biocompatibility, biodegradability, and hemostatic effect. However, most of them fail to …