Acetaminophen-induced nephrotoxicity: suppression of apoptosis and endoplasmic reticulum stress using boric acid

FK Çoban, S İnce, HH Demirel, İ İslam… - Biological Trace Element …, 2023 - Springer
Acetaminophen (APAP) is one of the popular and safe pain medications worldwide.
However, due its wide availability, it is frequently implicated in intentional or unintentional …

Boric acid is associated with the suppression of apoptosis and endoplasmic reticulum stress in rat model of paracetamol-induced hepatotoxicity

F Karabağ, S İnce, HH Demirel - Journal of Taibah University for …, 2023 - Taylor & Francis
Paracetamol (also known as acetaminophen or APAP) is an analgesic and antipyretic drug
that is widely used all over the world. Boron is an element proven by many studies that it has …

Sodium pentaborate prevents acetaminophen-induced hepatorenal injury by suppressing oxidative stress, lipid peroxidation, apoptosis, and inflammatory cytokines in …

E Aktas Senocak, N Utlu, S Kurt, S Kucukler… - … Trace Element Research, 2024 - Springer
Abstract Acetaminophen (N-acetyl-p-aminophenol, APAP, or paracetamol) is one of the
drugs that may be damaging to the kidneys and liver when used in excess. In this context, it …

The effect of boric acid and borax on oxidative stress, inflammation, ER stress and apoptosis in cisplatin toxication and nephrotoxicity developing as a result of …

Ö Hazman, MF Bozkurt, AF Fidan, FE Uysal, S Çelik - Inflammation, 2018 - Springer
The development of treatment protocols that can reduce side effects in chemotherapy
applications is extremely important in terms of cancer treatment. In this context, it was aimed …

Investigation of the protective effects of boric acid on ethanol induced kidney injury

E Cikler-Dulger, I Sogut - Biotechnic & Histochemistry, 2020 - Taylor & Francis
Boric acid (BA) is used as an antioxidant and anti-inflammatory agent, and for regulating
mitochondrial membrane potential in many disorders. We investigated the protective effects …

Investigation of boron effect on trace elements and antioxidant capacity in paracetamol-induced nephrotoxicity model

E Özkan, F Karabağ - Veteriner Hekimler Derneği Dergisi, 2020 - dergipark.org.tr
In this study, the effect of boron on the trace element and antioxidant capacity in paracetamol
induced nephrotoxicity model was investigated. The main hypothesis on which the study is …

[PDF][PDF] Investigation of the effects of boron on a renal ischemia/reperfusion injury in rats

TB Saritaş, H Saritaş, M Korkmaz, MF Bozkurt… - Int. J. Clin. Exp …, 2019 - e-century.us
Purpose: This study was intended to investigate the effects of boron on a rat renal
ischemia/reperfusion (I/R) damage model on biochemical and histopathological grounds …

Protective effects of boron on cyclophosphamide-induced bladder damage and oxidative stress in rats

A Ayhanci, DT Tanriverdi, V Sahinturk… - Biological trace element …, 2020 - Springer
This study aims to investigate protective effects of boron against cyclophosphamide-induced
bladder toxicity that produces oxidative stress and leads to apoptosis of the cells. In total, 24 …

Therapeutic role of boron on acrylamide-induced nephrotoxicity, cardiotoxicity, neurotoxicity, and testicular toxicity in rats: Effects on Nrf2/Keap-1 signaling pathway …

F Gür, M Cengiz, B Gür, O Cengiz, O Sarıçiçek… - Journal of Trace …, 2023 - Elsevier
Background Acrylamide (ACR) is a heat-related carcinogen used in cooking some foods as
well as in other thermal treatments. The present study aims to investigate the possible …

Assessment of the effect of sodium tetraborate on oxidative stress, inflammation, and apoptosis in lead-induced nephrotoxicity

T Yaman, HT Akkoyun… - Drug and Chemical …, 2024 - Taylor & Francis
Exposure to Pb, a toxic heavy metal, is a risk factor for renal damage. Borax, an essential
trace element in cellular metabolism, is a naturally occurring compound found in many …