Periventricular leukomalacia (PVL), the major substrate of cerebral palsy in survivors of
prematurity, is defined as focal periventricular necrosis and diffuse gliosis in immature …

Periventricular leukomalacia (PVL), the main substrate for cerebral palsy, is characterized by
diffuse injury of deep cerebral white matter, accompanied in its most severe form by focal …

Periventricular leukomalacia (PVL) is the major substrate of cerebral palsy in survivors of
prematurity. Its pathogenesis is complex and likely involves ischemia/reperfusion in the …

Periventricular leukomalacia in the premature infant is a lesion of cerebral white matter with
its greatest period of risk when white matter is immature, that is, when oligodendrocyte …

Reactive nitrogen species are thought to be involved in both hypoxic‐ischemic and cytokine‐
induced brain injury, including periventricular leukomalacia (PVL), the major pathological …

Periventricular leukomalacia (PVL), the major lesion underlying cerebral palsy in survivors
of prematurity, is characterized by focal periventricular necrosis and diffuse gliosis of …

Animal models have assisted in understanding the mechanisms of brain injury underlying
cerebral palsy. Nevertheless, no such models replicate every aspect of the human disease …

Periventricular leukomalacia (PVL) is the predominant form of brain injury and the leading
known cause of cerebral palsy and cognitive deficits in premature infants. The number of low …

Brain injury in the premature infant is a problem of enormous importance. Periventricular
leukomalacia (PVL) is the major neuropathologic form of this brain injury and underlies most …

Periventricular leukomalacia (PVL) occurring in premature infants, represents a major
precursor for neurological and intellectual impairment, and cerebral palsy in later life. The …