It is difficult to translate results from animal research on addiction to an understanding of the
behavior of human drug users. Despite decades of basic research on neurobiological …

Little is known about how social factors contribute to neurobiology or neuropsychiatric
disorders. The use of mice allows one to probe the neurobiological bases of social …

Addiction treatment has not been appreciably improved by neuroscientific research. One
problem is that mechanistic studies using rodent models do not incorporate volitional social …

Background We recently reported that operant social choice–induced voluntary abstinence
prevents incubation of methamphetamine craving. Here, we determined whether social …

Social reinforcement-based treatments are effective for many, but not all, people with
addictions to drugs. We recently developed an operant rat model that mimics features of one …

Until recently, most modern neuroscience research on addiction using animal models did
not incorporate manipulations of social factors. Social factors play a critical role in human …

The interaction between social factors and alcohol addiction is complex, with potential for
both positive and negative contributions to drug use and abstinence. Positive social …

Rationale and objective Social factors play a critical role in drug addiction. We recently
showed that rats will abstain from methamphetamine, cocaine, heroin, and remifentanil self …

Background Mouse models of social behavior fail to account for volitional aspects of social
interaction, and current neurobiological investigation of social behavior is performed almost …

Rationale One problem facing animal models of intravenous drug self-administration,
particularly those examining social manipulations, is that subjects must be removed from the …