Depression and epilepsy: epidemiologic and neurobiologic perspectives that may explain their high comorbid occurrence

AM Kanner, SC Schachter, JJ Barry, DC Hersdorffer… - Epilepsy & Behavior, 2012 - Elsevier
Depression is the most frequent psychiatric comorbidity in people with epilepsy (PWE) with
lifetime prevalence rates ranging between 30 and 35%. Multifactorial variables play a …

Depression in epilepsy: a neurobiologic perspective

AM Kanner - Epilepsy currents, 2005 - journals.sagepub.com
Depression is the most frequent psychiatric comorbidity in patients with epilepsy. By the
same token, patients with depression are at higher risk of developing epilepsy than are …

[HTML][HTML] Biomarkers of epileptogenesis: psychiatric comorbidities (?)

AM Kanner, A Mazarati, M Koepp - Neurotherapeutics, 2014 - Elsevier
The last decade has witnessed a significant shift on our understanding of the relationship
between psychiatric disorders and epilepsy. While traditionally psychiatric disorders were …

Depression and epilepsy: a review of multiple facets of their close relation

AM Kanner - Neurologic clinics, 2009 - neurologic.theclinics.com
Today, the study of depressive disorders in epilepsy no longer is restricted to an
understanding of psychosocial causes but includes an incorporation of the recent advances …

Is major depression a neurologic disorder with psychiatric symptoms?

AM Kanner - Epilepsy & behavior, 2004 - Elsevier
In the last decade, multiple investigator groups have identified structural changes of various
neuroanatomic structures in patients with idiopathic major depression and bipolar disorders …

Neuropsychiatric complications of epilepsy

AM Kanner, S Palac - Current neurology and neuroscience reports, 2002 - Springer
Psychiatric complications of epilepsy are multiple and result from the complex interaction
between endogenous, genetic, therapeutic, and environmental factors. The relationship …

Depression and epilepsy: how closely related are they?

AM Kanner, A Balabanov - Neurology, 2002 - AAN Enterprises
Depressive disorders (DDs) are the most common type of psychiatric co-morbidity in patients
with epilepsy. They are more likely to occur in patients with partial seizure disorders of …

[HTML][HTML] Diagnosing and treating depression in epilepsy

CE Elger, SA Johnston, C Hoppe - Seizure, 2017 - Elsevier
At least one third of patients with active epilepsy suffer from significant impairment of their
emotional well-being. A targeted examination for possible depression (irrespective of any …

Common pathogenic mechanisms between depression and epilepsy: an experimental perspective

PC Jobe - Epilepsy & Behavior, 2003 - Elsevier
Affective disorders and the epilepsies appear to share partially similar pathogenic
mechanisms. Predisposition to both disorders is determined genetically and experientially. A …

Mood disorder and epilepsy: a neurobiologic perspective of their relationship

AM Kanner - Dialogues in clinical neuroscience, 2008 - Taylor & Francis
Mood disorders are the most frequent psychiatric comorbidity in epilepsy, and in particular in
temporal lobe epilepsy. For a long time, depressive disorders were considered to be the …