Ezh2 is involved in radial neuronal migration through regulating Reelin expression in cerebral cortex

L Zhao, J Li, Y Ma, J Wang, W Pan, K Gao, Z Zhang… - Scientific reports, 2015 - nature.com
Radial migration of pyramidal neurons is an important event during the development of
cerebral cortex. Neurons experience series of morphological and directional transitions to …

Reelin signaling in the migration of ventral brain stem and spinal cord neurons

AR Vaswani, S Blaess - Frontiers in cellular neuroscience, 2016 - frontiersin.org
The extracellular matrix protein Reelin is an important orchestrator of neuronal migration
during the development of the central nervous system. While its role and mechanism of …

Control of neuronal migration and aggregation by reelin signaling in the developing cerebral cortex

Y Hirota, K Nakajima - Frontiers in cell and developmental biology, 2017 - frontiersin.org
The mammalian cerebral neocortex has a well-organized laminar structure, achieved by the
highly coordinated control of neuronal migration. During cortical development, excitatory …

How does Reelin control neuronal migration and layer formation in the developing mammalian neocortex?

K Sekine, K Kubo, K Nakajima - Neuroscience research, 2014 - Elsevier
The mammalian neocortex has a laminar structure that develops in a birth-date-dependent
“inside-out” pattern. Its layered structure is established by neuronal migration accompanied …

Reelin prevents apical neurite retraction during terminal translocation and dendrite initiation

RS O'Dell, DA Cameron, WR Zipfel… - Journal of …, 2015 - Soc Neuroscience
The mechanisms controlling cortical dendrite initiation and targeting are poorly understood.
Multiphoton imaging of developing mouse cortex reveals that apical dendrites emerge by …

Repurposing Reelin: The new role of radial glia, Reelin and Notch in motor neuron migration

AL Hawthorne - Experimental neurology, 2014 - Elsevier
The role of Reelin during cerebral cortical neuron migration has long been studied, but the
Reelin signaling pathway and its possible interactions are just beginning to be unraveled …

Go or stop? Divergent roles of Reelin in radial neuronal migration

S Zhao, M Frotscher - The Neuroscientist, 2010 - journals.sagepub.com
Neuronal migration is an essential step of brain development and is controlled by a variety
of cellular proteins and extracellular matrix molecules. Reelin, an extracellular matrix …

ApoER2 controls not only neuronal migration in the intermediate zone but also termination of migration in the developing cerebral cortex

Y Hirota, K Kubo, T Fujino, TT Yamamoto… - Cerebral …, 2018 - academic.oup.com
Neuronal migration contributes to the establishment of mammalian brain. The extracellular
protein Reelin sends signals to various downstream molecules by binding to its receptors …

Trajectory analysis unveils Reelin's role in the directed migration of granule cells in the dentate gyrus

S Wang, B Brunne, S Zhao, X Chai, J Li… - Journal of …, 2018 - Soc Neuroscience
Reelin controls neuronal migration and layer formation. Previous studies in reeler mice
deficient in Reelin focused on the result of the developmental process in fixed tissue …

An In Silico Agent-Based Model Demonstrates Reelin Function in Directing Lamination of Neurons during Cortical Development

JR Caffrey, BD Hughes, JM Britto, KA Landman - PloS one, 2014 - journals.plos.org
The characteristic six-layered appearance of the neocortex arises from the correct
positioning of pyramidal neurons during development and alterations in this process can …