Exosomes and the invariant NKT (iNKT) immune cell ligand α-galactosylceramide (αGC)
may offer novel tools for cancer immunotherapy. In this study, we investigated whether …

Exosomes (EXOs) derived from tumor cells have been used to stimulate antitumor immune
responses. It has been demonstrated that EXO released by tumor cells engineered to …

Despite multiple immunotherapeutic technologies that achieve potent T cell activation,
effector T cells still lack efficiency because of the highly immunosuppressive conditions in …

Abstract MVA-BN-PRO (BN ImmunoTherapeutics) is a candidate immunotherapy product for
the treatment of prostate cancer. It encodes 2 tumor-associated antigens, prostate-specific …

Extracellular vesicles (EVs), including endosome-derived nanovesicles (exosomes), are
involved in cell–cell communication. Through transfer of their molecular contents …

Tumor cell-derived exosomes (TEX) have been widely used to induce antitumor immune
responses in animal models and clinical trials. However, the efficiency of the antitumor …

Peptide-loaded exosomes are promising cancer treatment vehicles; however, moderate T
cell responses in human clinical trials indicate a need to further understand exosome …

Exosomes are membranous vesicles actively secreted by almost all cells and they deliver
certain intracellular molecules, including nucleic acids, proteins, and lipids, to target cells …

Exosomes, as a subset of extracellular vesicles, function as a mode of intercellular
communication and molecular transfer, and facilitate the direct extracellular transfer of …

In recent years exosomes have emerged as potent stimulators of immune responses and as
agents for cancer therapy. Exosomes can carry a broad variety of immunostimulatory …