Jatrorrhizine Alleviates DSS‐Induced Ulcerative Colitis by Regulating the Intestinal Barrier Function and Inhibiting TLR4/MyD88/NF‐κB Signaling Pathway

S Niu, M Jing, J Wen, S Wei, H Li, X Li… - Evidence‐Based …, 2022 - Wiley Online Library
Background. Ulcerative colitis (UC), a kind of autoimmune disease with unknown etiology,
has been troubling human physical and mental health. Jatrorrhizine (Jat) is a natural …

Daurisoline alleviated experimental colitis in vivo and in vitro: Involvement of NF-κB and Wnt/β-Catenin pathway

J Zhou, H Wu, J Hou, J Wang, J Wang, M Li… - International …, 2022 - Elsevier
Daurisoline (DS) is one of the most abundant alkaloids extracted from the rhizome of
Menispermum Dauricum DC, which is traditionally used to treat inflammatory diseases …

Huangkui Lianchang Decoction Ameliorates DSS‐Induced Ulcerative Colitis in Mice by Inhibiting the NF‐kappaB Signaling Pathway

Z He, Q Zhou, K Wen, B Wu, X Sun… - Evidence‐Based …, 2019 - Wiley Online Library
Background. The nuclear factor kappa beta (NF‐κB) signaling pathway plays an important
role in ulcerative colitis (UC). Huangkui Lianchang decoction (HLD) is an effective traditional …

Jatrorrhizine alleviates ulcerative colitis via regulating gut microbiota and NOS2 expression

JL Zhang, MN Zhang, HG Wang, XZ Yang, CG Yu - Gut pathogens, 2022 - Springer
Background The natural protoberberine jatrorrhizine (JA) is reported to have several
medicinal properties and a significant effect on the gut microbiota of mice. The regulation of …

Ethanol extract of Piper wallichii ameliorates DSS-induced ulcerative colitis in mice: involvement of TLR4/NF-κB/COX-2 signaling pathway

J Zhao, R Wu, P Wei, Z Ma, H Pei, J Hu, F Wen… - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance Piper wallichii (family: Piperaceae), a folk herbal medicine
with anti-inflammatory and anti-thrombotic properties, has been traditionally used to treat …

Preventive effect of Atractylodis Rhizoma extract on DSS-induced acute ulcerative colitis through the regulation of the MAPK/NF-κB signals in vivo and in vitro

X Lin, X Guo, L Qu, J Tu, S Li, G Cao, Y Liu - Journal of Ethnopharmacology, 2022 - Elsevier
Abstract Ethnopharmacological relevance Atractylodes lancea (Thunb.) DC. is traditionally
used as a folk medicine for treating gastrointestinal diseases in China. Nevertheless, the …

Sanhuang Xiexin decoction ameliorates DSS-induced colitis in mice by regulating intestinal inflammation, intestinal barrier, and intestinal flora

X Wu, S Fu, M Jiang, J Wang, H Tang, C Fang… - Journal of …, 2022 - Elsevier
Abstract Ethnopharmacological relevance Sanhuang Xiexin decoction (SXD) is a widely
applicated traditional Chinese medicine (TCM) with a significant intestinal anti-inflammatory …

Salvia miltiorrhiza stems and leaves total phenolic acids combination with tanshinone protect against DSS-induced ulcerative colitis through inhibiting TLR4/PI3K/AKT …

KY Peng, JF Gu, SL Su, Y Zhu, JM Guo… - Journal of …, 2021 - Elsevier
Ethnopharmacological relevance Salvia miltiorrhiza Bge. as a traditional Asian medicinal
plant, roots and rhizomes (Danshen) are used to treat chronic hepatitis and coronary heart …

[HTML][HTML] Phillygenin attenuated colon inflammation and improved intestinal mucosal barrier in DSS-induced colitis mice via TLR4/Src mediated MAPK and NF-κB …

HH Xue, JJ Li, SF Li, J Guo, RP Yan, TG Chen… - International Journal of …, 2023 - mdpi.com
Ulcerative colitis (UC) is a chronic, relapsing, and nonspecific inflammatory bowel disease
(IBD). Phillygenin (PHI), a natural bioactive ingredient, isolated from Forsythiae Fructus …

Naringin exhibited therapeutic effects against DSS-induced mice ulcerative colitis in intestinal barrier–dependent manner

R Cao, X Wu, H Guo, X Pan, R Huang, G Wang, J Liu - Molecules, 2021 - mdpi.com
Naringin is a kind of multi-source food additive which has been explored broadly for its
various biological activities and therapeutic potential. In the present study, the protective …