Resident stem cells and renal carcinoma

B Bussolati, A Brossa, G Camussi - International journal of …, 2011 - Wiley Online Library
According to the cancer stem cell hypothesis tumors are maintained by a cancer stem cell
population which is able to initiate and maintain tumors. Tumor‐initiating stem cells display …

Renal stem cells and their implications for kidney cancer

H Axelson, ME Johansson - Seminars in cancer biology, 2013 - Elsevier
The renal cell carcinomas (RCC) denote a diverse set of neoplasias with unique genetic and
histological features. The RCCs emanate from the renal tubule, a highly heterogeneous …

Human renal cancer stem cells

B Bussolati, B Dekel, B Azzarone, G Camussi - Cancer Letters, 2013 - Elsevier
Cancer stem cells (CSCs), isolated in renal carcinomas, exhibit tumor-initiating capabilities
and pluripotency. No specific CSC markers have been identified so far; therefore, their …

Identification of a tumor‐initiating stem cell population in human renal carcinomas

B Bussolati, S Bruno, C Grange, U Ferrando… - The FASEB …, 2008 - Wiley Online Library
The purpose of the present study was to search for the presence of a tumor‐initiating stem
cell population in renal carcinomas. Based on the recent identification of mesenchymal stem …

Cancer stem cells in renal cell carcinoma: origins and biomarkers

F Lasorsa, M Rutigliano, M Milella, M Ferro… - International Journal of …, 2023 - mdpi.com
The term “cancer stem cell”(CSC) refers to a cancer cell with the following features:
clonogenic ability, the expression of stem cell markers, differentiation into cells of different …

CD133+ renal progenitor cells contribute to tumor angiogenesis

S Bruno, B Bussolati, C Grange, F Collino… - The American journal of …, 2006 - Elsevier
In the present study, we tested the hypothesis that resident progenitor cells may contribute to
tumor vascularization and growth. CD133+ cells were isolated from 30 human renal …

Isolation and characterization of cancer stem cells in renal cell carcinoma

G Lucarelli, V Galleggiante, M Rutigliano… - Urologia …, 2015 - journals.sagepub.com
Recently, several studies have investigated the presence of cancer stem cells in kidney
cancer, performed characterization, and compared their profile with the normal stem cell …

Current approaches in identification and isolation of human renal cell carcinoma cancer stem cells

MI Khan, AM Czarnecka, I Helbrecht, E Bartnik… - Stem cell research & …, 2015 - Springer
In recent years, cancer stem cells (CSCs)/tumor initiating cells (TICs) have been identified
inside different tumors. However, currently used anti-cancer therapies are mostly directed …

Renal cancer stem cells: characterization and targeted therapies

AJ Peired, A Sisti, P Romagnani - Stem cells international, 2016 - Wiley Online Library
Renal cell carcinoma (RCC) is a major neoplasm with high incidence in western countries.
Tumors are heterogeneous and are composed of differentiated cancer cells, stromal cells …

Cancer stem cells in urologic cancers

C Gedye, AJ Davidson, MR Elmes, J Cebon… - … Oncology: Seminars and …, 2010 - Elsevier
There is evolving evidence for the so-called cancer stem cell (CSC) hypothesis, which holds
that intra-tumoral heterogeneity in urologic malignancies is hierarchical and that not all cells …