Blinding and expectancy confounds in psychedelic randomized controlled trials
SD Muthukumaraswamy, A Forsyth… - Expert review of clinical …, 2021 - Taylor & Francis
Introduction: There is increasing interest in the potential for psychedelic drugs such as
psilocybin, LSD and ketamine to treat several mental health disorders, with a growing …
psilocybin, LSD and ketamine to treat several mental health disorders, with a growing …
Expectancy in placebo-controlled trials of psychedelics: if so, so what?
Modern psychedelic research remains in an early phase, and the eventual introduction of
psychedelics into clinical practice remains in doubt. In this piece, we discuss the role of …
psychedelics into clinical practice remains in doubt. In this piece, we discuss the role of …
Risk of bias in randomized clinical trials on psychedelic medicine: A systematic review
OR Hovmand, ED Poulsen, S Arnfred… - Journal of …, 2023 - journals.sagepub.com
Background: The classical psychedelics, psilocybin, peyote, ayahuasca/N, N-
dimethyltryptamine, and lysergic acid diethylamide are considered promising new …
dimethyltryptamine, and lysergic acid diethylamide are considered promising new …
Great Expectations: recommendations for improving the methodological rigor of psychedelic clinical trials
Rationale Psychedelic research continues to garner significant public and scientific interest
with a growing number of clinical studies examining a wide range of conditions and …
with a growing number of clinical studies examining a wide range of conditions and …
Control conditions in randomized trials of psychedelics: an ACTTION systematic review
SM Nayak, MK Bradley, BA Kleykamp… - The Journal of clinical …, 2023 - psychiatrist.com
Results: In total, 126 articles were included, encompassing 86 unique studies. Of studies
with a drug control condition (80), 49 (61.2%) used an inert placebo control, 16 (20.0%) …
with a drug control condition (80), 49 (61.2%) used an inert placebo control, 16 (20.0%) …
Should we be leery of being Leary? Concerns about psychedelic use by psychedelic researchers
B Kious, Z Schwartz, B Lewis - Journal of …, 2023 - journals.sagepub.com
Psychedelic research is proceeding rapidly, despite ongoing legal and regulatory barriers
and lingering questions about study design, such as the difficulty of ensuring adequate …
and lingering questions about study design, such as the difficulty of ensuring adequate …
History repeating: guidelines to address common problems in psychedelic science
Research in the last decade has expressed considerable optimism about the clinical
potential of psychedelics for the treatment of mental disorders. This optimism is reflected in …
potential of psychedelics for the treatment of mental disorders. This optimism is reflected in …
Can pragmatic research, real-world data and digital technologies aid the development of psychedelic medicine?
RL Carhart-Harris, AC Wagner… - Journal of …, 2022 - journals.sagepub.com
Favourable regulatory assessments, liberal policy changes, new research centres and
substantial commercial investment signal that psychedelic therapy is making a major …
substantial commercial investment signal that psychedelic therapy is making a major …
The challenges ahead for psychedelic 'medicine'
S Muthukumaraswamy, A Forsyth… - Australian & New …, 2022 - journals.sagepub.com
With the extensive public, commercial and scientific interest from what has been widely
termed the psychedelic renaissance, it is important that the scientific practices and results …
termed the psychedelic renaissance, it is important that the scientific practices and results …
Predicting responses to psychedelics: a prospective study
Responses to psychedelics are notoriously difficult to predict, yet significant work is currently
underway to assess their therapeutic potential and the level of interest in psychedelics …
underway to assess their therapeutic potential and the level of interest in psychedelics …