The endocannabinoid system and cancer: therapeutic implication

J Guindon, AG Hohmann - British journal of pharmacology, 2011 - Wiley Online Library
The endocannabinoid system is implicated in a variety of physiological and pathological
conditions (inflammation, immunomodulation, analgesia, cancer and others). The main …

Anti‐tumour actions of cannabinoids

B Hinz, R Ramer - British journal of pharmacology, 2019 - Wiley Online Library
The endocannabinoid system has emerged as an important target for the treatment of many
diverse diseases. In addition to the well‐established palliative effects of cannabinoids in …

The endocannabinoid system in cancer—Potential therapeutic target?

J Flygare, B Sander - Seminars in cancer biology, 2008 - Elsevier
Endogenous arachidonic acid metabolites with properties similar to compounds of Cannabis
sativa Linnaeus, the so-called endocannabinoids, have effects on various types of cancer …

Cannabinoids and cancer: pros and cons of an antitumour strategy

M Bifulco, C Laezza, S Pisanti… - British journal of …, 2006 - Wiley Online Library
In the last two decades, research has dramatically increased the knowledge of cannabinoids
biology and pharmacology. In mammals, compounds with properties similar to active …

Insights into the effects of the endocannabinoid system in cancer: a review

AI Fraguas‐Sánchez, C Martín‐Sabroso… - British journal of …, 2018 - Wiley Online Library
In the last few decades, the endocannabinoid system has attracted a great deal of interest in
terms of its applications to clinical medicine. In particular, its applications in cancer probably …

Cannabinoids, endocannabinoids, and cancer

DJ Hermanson, LJ Marnett - Cancer and metastasis reviews, 2011 - Springer
The endocannabinoid system consists of an array of endogenously produced bioactive
lipids that activate cannabinoid receptors. Although the primary focus of endocannabinoid …

Cannabinoids as anticancer drugs: current status of preclinical research

B Hinz, R Ramer - British journal of cancer, 2022 - nature.com
Drugs that target the endocannabinoid system are of interest as pharmacological options to
combat cancer and to improve the life quality of cancer patients. From this perspective …

Update on the endocannabinoid system as an anticancer target

AM Malfitano, E Ciaglia, G Gangemi… - Expert opinion on …, 2011 - Taylor & Francis
Introduction: Recent studies have shown that the endocannabinoid system (ECS) could offer
an attractive antitumor target. Numerous findings suggest the involvement of this system …

Endocannabinoid system modulation in cancer biology and therapy

S Pisanti, M Bifulco - Pharmacological research, 2009 - Elsevier
The discovery of the endocannabinoid system and the recognition of its potential impact in a
plethora of pathological conditions, led to the development of therapeutic agents related to …

Cannabinoids as anticancer drugs

R Ramer, B Hinz - Advances in Pharmacology, 2017 - Elsevier
The endocannabinoid system encompassing cannabinoid receptors, endogenous receptor
ligands (endocannabinoids), as well as enzymes conferring the synthesis and degradation …