Abstract Purpose of the Review Causality has been demonstrated for few of the many
putative risk factors for type 2 diabetes (T2D) emerging from observational epidemiology …

Abstract Purpose of Review Genome-wide association studies have delineated the genetic
architecture of type 2 diabetes. While functional studies to identify target transcripts are …

Background The prevalence and incidence of type 2 diabetes (T2D), representing> 90% of
all cases of diabetes, are increasing rapidly worldwide. Identification of individuals at high …

Abstract Purpose of Review Type 2 diabetes (T2D) is a multifactorial, heritable syndrome
characterized by dysregulated glucose homeostasis that results from impaired insulin …

Abstract Knowledge of the genetics of type 2 diabetes mellitus (T2DM) has evolved
tremendously over the past few years. Following advances in technology and analytical …

Since 2007, genome-wide association studies have rapidly increased the number of T2D-
associated loci. This review summarizes the history of genetic association studies, the …

Over the past 8 years, the genetics of complex traits have benefited from an unprecedented
advancement in the identification of common variant loci for diseases such as type 2 …

Abstract Type 2 diabetes (T2D) is epidemic, but much has been learned about its molecular
etiology in recent years. In this review, we present the substantial evidence for the …

Type 2 diabetes (T2D) is a complex disease that is caused by a complex interplay between
genetic, epigenetic and environmental factors. While the major environmental factors, diet …

Insights into type 1 diabetes provided by genetic analyses : Current Opinion in Endocrinology,
Diabetes and Obesity Insights into type 1 diabetes provided by genetic analyses : Current …