Macrophages are key cellular components of innate immunity, acting as the first line of
defense against pathogens to modulate homeostatic and inflammatory responses. They …

The fungal pathogen Cryptococcus neoformans can cause life-threatening infections in
immune compromised individuals. This pathogen is typically acquired via inhalation, and …

Cryptococcus species are encapsulated fungi found in the environment that predominantly
cause disease in immunocompromised hosts after inhalation into the lungs. Even with …

Cryptococcus species are fungal pathogens that are a leading cause of mortality. Initial
inoculation is through the pulmonary route and, if disseminated, results in severe invasive …

Cryptococcus infections represents a major healthcare burden, with over 200,000 cases
globally a year and even with treatment, mortality remains as high as 80%. There is a clear …

Cryptococcus neoformans and C. gattii are fungal pathogens that cause life-threatening
disease. These fungi commonly enter their host via inhalation into the lungs where they …

Cryptococcus neoformans (Cn) is a fungal pathogen that is a serious health threat to
immunocompromised individuals. Upon environmental exposure, infectious fungal …

Cryptococcus neoformans is an opportunistic fungal pathogen that causes over 180,000
annual deaths in HIV/AIDS patients. Innate phagocytes in the lungs, such as dendritic cells …

Abstract Background/Aims: Cryptococcus neoformans infections are becoming increasingly
prevalent and remain a life-threatening clinical issue in immune-compromised hosts. The …

The fungal pathogens Cryptococcus neoformans and Cryptococcus gattii can cause life-
threatening infections in immune compromised and immune competent hosts. These …