Organoids, which exhibit spontaneous organ specific organization, function, and multi-
cellular complexity, are in essence the in vitro reproduction of specific in vivo organ systems …

Human pluripotent stem cell (hPSC)-derived islet cells provide promising resources for
diabetes studies, cell replacement treatment and drug screening. Recently, hPSC-derived …

Human adult stem cells and patient-derived induced pluripotent stem cells represent
promising tools to understand human biology, development, and disease. Under a …

Organoids derived from self‐organizing stem cells represent a major technological
breakthrough with the potential to revolutionize biomedical research. However, building high …

Human organoids are emerging as a valuable resource to investigate human organ
development and disease. The applicability of human organoids has been limited, partly …

Temporal manipulation of the in vitro environment and growth factors can direct
differentiation of human pluripotent stem cells into organoids–aggregates with multiple …

Three-dimensional organoids derived from human pluripotent stem cell (hPSC) derivatives
have become widely used in vitro models for studying development and disease. Their …

Organoids are in vitro cultures of miniature fetal or adult organ-like structures. Their
potentials for use in tissue and organ replacement, disease modeling, toxicology studies …

Regenerating human islet organoids from stem cells remains a significant challenge
because of our limited knowledge on cues essential for developing the endocrine organoids …

Organoids are miniature models of organs to recapitulate spatiotemporal cellular
organization and tissue functionality. The production of organoids has revolutionized the …