Diagnostic role of microRNA expression profile in the serum of pregnant women with fetuses with neural tube defects

H Gu, H Li, L Zhang, H Luan, T Huang… - Journal of …, 2012 - Wiley Online Library
J. Neurochem.(2012) 122, 641–649. Abstract The discovery of placental microRNAs
(miRNAs) in maternal serum has opened up new possibilities for non‐invasive prenatal …

Identification of pregnancy-associated microRNAs in maternal plasma

K Miura, S Miura, K Yamasaki, A Higashijima… - Clinical …, 2010 - academic.oup.com
BACKGROUND Several placental microRNAs (miRNAs) have been identified as pregnancy-
associated molecules with the potential for use in estimating the condition of the placenta …

MicroRNAs: potential regulators involved in human anencephaly

Z Zhang, H Chang, Y Li, T Zhang, J Zou… - The international journal …, 2010 - Elsevier
MicroRNAs (miRNAs) are posttranscriptional regulators of messenger RNA activity. Neural
tube defects (NTDs) are severe congenital anomalies that substantially impact an infant's …

Detection and characterization of placental microRNAs in maternal plasma

SSC Chim, TKF Shing, ECW Hung, T Leung… - Clinical …, 2008 - academic.oup.com
Background: The discovery of circulating fetal nucleic acids in maternal plasma has opened
up new possibilities for noninvasive prenatal diagnosis. MicroRNAs (miRNAs), a class of …

A comprehensive survey of maternal plasma miRNAs expression profiles using high-throughput sequencing

H Li, L Guo, Q Wu, JF Lu, Q Ge, Z Lu - Clinica Chimica Acta, 2012 - Elsevier
OBJECTIVE: Recently, microRNAs (miRNAs) had been shown as potential important
regulators in pregnancy. Circulating miRNAs are considered as potentially useful non …

[HTML][HTML] Differential expression of circulating miRNAs in maternal plasma in pregnancies with fetal macrosomia

Q Ge, Y Zhu, H Li, F Tian, X Xie… - … Journal of Molecular …, 2015 - spandidos-publications.com
Macrosomia is associated with problems at birth and has life-long health implications for the
infant. The aim of this study was to profile the plasma microRNAs (miRNAs or miRs) and …

[HTML][HTML] Profiling circulating microRNAs in maternal serum and plasma

Q Ge, Y Shen, F Tian, J Lu… - Molecular Medicine …, 2015 - spandidos-publications.com
Serum and plasma are two of the most commonly used materials in clinical diagnosis and
investigations. Whether differential nucleic acids exist between the serum and plasma, and …

[HTML][HTML] Expression profile of maternal circulating microRNAs as non-invasive biomarkers for prenatal diagnosis of congenital heart defects

H Gu, L Chen, J Xue, T Huang, X Wei, D Liu… - Biomedicine & …, 2019 - Elsevier
Objective The discovery of cell free fetal microRNAs (miRNAs) in maternal circulation has
opened up novel probabilities for non-invasive prenatal diagnosis. This study aims to …

Identification of maternal serum microRNAs as novel non-invasive biomarkers for prenatal detection of fetal congenital heart defects

S Zhu, L Cao, J Zhu, L Kong, J Jin, L Qian, C Zhu… - Clinica chimica acta, 2013 - Elsevier
Background Congenital heart defects (CHD) are the most common form of malformation
during embryonic development. Circulating miRNAs have recently been shown to serve as …

[HTML][HTML] Genome-wide microRNA profiling in human fetal nervous tissues by oligonucleotide microarray

JJ Zhao, YJ Hua, DG Sun, XX Meng, HS Xiao… - Child's Nervous …, 2006 - Springer
Abstract Objects Our objective was to develop an oligonucleotide DNA microarray (OMA) for
genome-wide microRNA profiling and use this method to find miRNAs, which control organic …