Migraine, a debilitating neurological condition, significantly affects patients' quality of life.
Fenofibrate, a peroxisome proliferator-activated receptor alpha (PPAR-α) agonist approved …

Background As a complex nervous system disease, migraine causes severe healthy and
social issues worldwide. Valproate (VPA) is a widely used treatment agent against seizures …

Background Oxidative stress and inflammatory pathways are involved in migraine and
endogenous antioxidant defense system has a role in the prevention of hyperalgesia in …

Migraine causes severe health and social issues worldwide. Rhynchophylline (Rhy) is one
of the major active components of Uncaria rhynchophylla that is used for the treatment of …

Background Migraine stands as a prevalent primary headache disorder, with prior research
highlighting the significant involvement of oxidative stress and inflammatory pathways in its …

Background and aim Infusion of glyceryltrinitrate (GTN), a nitric oxide (NO) donor, in awake,
freely moving rats closely mimics a universally accepted human model of migraine and …

The association between the clinical use of nitroglycerin (NTG) and migraine suggests NTG
as an animal model trigger for migraine. NTG-induced hyperalgesia in rats has been …

The purpose of this research was to explore the effect and mechanism of emodin in
interfering with nitroglycerin-induced migraine rats. We carried out behavioral research …

Migraine is a common neurological disorder with a serious impact on quality of life. The aim
of this study was to explore the effect of baicalin on nitroglycerin‐induced migraine rats. We …

Ethnopharmacological relevance Paeonol (PAE) and glycyrrhizic acid (GLY) are
predominate components of 14 blood-entering ones of Piantongtang No. 1, which is a …