Mechanism of epithelial‐mesenchymal transition in cancer and its regulation by natural compounds

HL Ang, CD Mohan, MK Shanmugam… - Medicinal research …, 2023 - Wiley Online Library
Epithelial‐mesenchymal transition (EMT) is a complex process with a primordial role in
cellular transformation whereby an epithelial cell transforms and acquires a mesenchymal …

Therapeutic implications of cancer epithelial-mesenchymal transition (EMT)

ES Cho, HE Kang, NH Kim, JI Yook - Archives of pharmacal research, 2019 - Springer
The epithelial-mesenchymal transition (EMT) comprises an essential biological process
involving cancer progression as well as initiation. While the EMT has been regarded as a …

The epithelial-to-mesenchymal transition in cancer

J Roche - Cancers, 2018 - mdpi.com
The epithelial-to-mesenchymal transition (EMT) occurs during normal embryonic
development, tissue regeneration, organ fibrosis, and wound healing. It is a highly dynamic …

Natural plants compounds as modulators of epithelial-to-mesenchymal transition

L Avila-Carrasco, P Majano… - Frontiers in …, 2019 - frontiersin.org
Epithelial-to-mesenchymal transition (EMT) is a self-regulated physiological process
required for tissue repair that, in non-controled conditions may lead to fibrosis …

Epithelial-mesenchymal transition and cell invasion

H Son, A Moon - Toxicological research, 2010 - Springer
Epithelial-mesenchymal transition (EMT) is a complex process in which epithelial cells
acquire the characteristics of invasive mesenchymal cells. EMT has been implicated in …

[HTML][HTML] Epithelial-mesenchymal transition in cancer: a historical overview

D Ribatti, R Tamma, T Annese - Translational oncology, 2020 - Elsevier
Abstract Epithelial-mesenchymal transitions (EMTs), the acquisition of mesenchymal
features from epithelial cells, occur during some biological processes and are classified into …

The molecular mechanisms and therapeutic strategies of EMT in tumor progression and metastasis

Y Huang, W Hong, X Wei - Journal of hematology & oncology, 2022 - Springer
Epithelial–mesenchymal transition (EMT) is an essential process in normal embryonic
development and tissue regeneration. However, aberrant reactivation of EMT is associated …

Small molecule inhibitors of epithelial‐mesenchymal transition for the treatment of cancer and fibrosis

YL Feng, DQ Chen, ND Vaziri, Y Guo… - Medicinal research …, 2020 - Wiley Online Library
Tissue fibrosis and cancer both lead to high morbidity and mortality worldwide; thus,
effective therapeutic strategies are urgently needed. Because drug resistance has been …

Epithelial-mesenchymal transition: focus on metastatic cascade, alternative splicing, non-coding RNAs and modulating compounds

TR Samatov, AG Tonevitsky, U Schumacher - Molecular cancer, 2013 - Springer
Epithelial-mesenchymal transition (EMT) is a key process in embryonic development and
metastases formation during malignant progression. This review focuses on transcriptional …

Epithelial-mesenchymal transition: implications in cancer progression and metastasis

LR Gomes, LF Terra, MC Sogayar… - Current …, 2011 - ingentaconnect.com
During the past few years, Epithelial-Mesenchymal Transition (EMT) has emerged as one of
the most hot spots in clinical research. Its existence in human tumors can form the basis for …