Prestin (SLC26A5)-mediated voltage-driven elongations and contractions of sensory outer
hair cells within the organ of Corti are essential for mammalian cochlear amplification …

Abstract Prestin (SLC26A5) is a membrane-based voltage-dependent motor protein
responsible for outer hair cell (OHC) somatic electromotility. Its importance for mammalian …

Outer hair cells (OHCs) are a mammalian innovation for mechanically amplifying sound
energy to overcome the viscous damping of the cochlear partition. Although the voltage …

It is a central tenet of cochlear neurobiology that mammalian ears rely on a local,
mechanical amplification process for their high sensitivity and sharp frequency selectivity …

Outer hair cells (OHC) of the mammalian cochlea exhibit electromotility that occurs at
acoustic frequencies and is thought to produce the amplification of vibrations required for the …

Normal hearing depends on sound amplification within the mammalian cochlea. The
amplification, without which the auditory system is effectively deaf, can be traced to the …

The solute carrier transmembrane protein prestin (SLC26A5) drives an active
electromechanical transduction process in cochlear outer hair cells that increases hearing …

Charged moieties in the outer hair cell (OHC) membrane motor protein, prestin, are driven
by transmembrane voltage to power OHC electromotility (eM) and cochlear amplification …

Non‐technical summary Cochlear inner hair cells transform acoustic signals into electric
signals. Another type of hair cells, outer hair cells, actively amplifies sensory signals and …

Abstract The House Ear Institute-Organ of Corti 1 (HEI-OC1) is a mouse auditory cell line
that endogenously express, among other several markers of cochlear hair cells, the motor …