Cryptococcus neoformans Infection in the Central Nervous System: The Battle between Host and Pathogen

Y Chen, ZW Shi, AB Strickland, M Shi - Journal of Fungi, 2022 - mdpi.com
Cryptococcus neoformans (C. neoformans) is a pathogenic fungus with a global distribution.
Humans become infected by inhaling the fungus from the environment, and the fungus …

Mechanisms of infection by the human fungal pathogen Cryptococcus neoformans

W Sabiiti, RC May - Future microbiology, 2012 - Future Medicine
Brain infection by the fungus Cryptococcus neoformans results in inflammation of the
meninges and brain parenchyma, a condition known as meningoencephalitis. One million …

The Biology of the Cryptococcus neoformans Species Complex

X Lin, J Heitman - Annu. Rev. Microbiol., 2006 - annualreviews.org
Cryptococcus neoformans is a major cause of fungal meningoencephalitis in
immunocompromised patients. Despite recent advances in the genetics and molecular …

Cryptococcus neoformans promotes its transmigration into the central nervous system by inducing molecular and cellular changes in brain endothelial cells

K Vu, RA Eigenheer, BS Phinney, A Gelli - Infection and Immunity, 2013 - Am Soc Microbiol
Cryptococcus spp. cause fungal meningitis, a life-threatening infection that occurs
predominately in immunocompromised individuals. In order for Cryptococcus neoformans to …

Cryptococcus neoformans α Strains Preferentially Disseminate to the Central Nervous System during Coinfection

K Nielsen, GM Cox, AP Litvintseva… - Infection and …, 2005 - Am Soc Microbiol
Cryptococcus neoformans is a fungal pathogen that has evolved over the past 40 million
years into three distinct varieties or sibling species (gattii, grubii, and neoformans). Each …

Microbe Profile: Cryptococcus neoformans species complex

YS Bahn, S Sun, J Heitman, X Lin - Microbiology, 2020 - microbiologyresearch.org
Cryptococcus neoformans is a lethal fungus disguised in a polysaccharide coat. It can
remain dormant in the host for decades prior to reactivation, causing systemic …

Dissemination of C. neoformans to the central nervous system: role of chemokines, Th1 immunity and leukocyte recruitment

GB Huffnagle, LK McNeil - Journal of neurovirology, 1999 - Taylor & Francis
Cryptococcus neoformans is a fungus that possesses two properties unique for yeast:(1)
production of a polysaccharide capsule and (2) neurotropism. The natural route of infection …

Intranasal inoculation of Cryptococcus neoformans in mice produces nasal infection with rapid brain dissemination

C Coelho, E Camacho, A Salas, A Alanio… - MSphere, 2019 - Am Soc Microbiol
Cryptococcus neoformans is an important fungal pathogen, causing life-threatening
pneumonia and meningoencephalitis. Brain dissemination of C. neoformans is thought to be …

Cryptococcus neoformans: morphogenesis, infection, and evolution

X Lin - Infection, Genetics and Evolution, 2009 - Elsevier
Cryptococcus neoformans is the major causative agent of fungal meningoencephalitis in
both immunocompromised and immunocompetent individuals. During infection, this fungus …

[HTML][HTML] Fungal colonization of the brain: anatomopathological aspects of neurological cryptococcosis

AC Colombo, ML Rodrigues - Anais da Academia Brasileira de …, 2015 - SciELO Brasil
Brain infection by the fungus Cryptococcus neoformans results in an estimated 500,000
human deaths per annum. Colonization of the central nervous system (CNS) by C …