The role of mammalian skin in harbouring and transmitting arthropod-borne protozoan
parasites has been overlooked for decades as these pathogens have been regarded …

Trypanosoma brucei is a protozoan parasite that causes human and animal African
trypanosomiases (HAT and AAT). In the mammalian host, the parasite lives entirely …

Background The diagnosis of gambiense human African trypanosomiasis (gHAT) typically
involves 2 steps: a serological screen, followed by the detection of living trypanosome …

Tsetse flies are the sole vectors of Trypanosoma brucei parasites that cause sleeping
sickness. Our knowledge on the early interface between the infective metacyclic forms and …

Parasitic diseases, such as sleeping sickness, Chagas disease and malaria, remain a major
cause of morbidity and mortality worldwide, but particularly in tropical, developing countries …

Oral transmission of Trypanosoma cruzi, the causative agent of Chagas disease, is the most
important route of infection in Brazilian Amazon and Venezuela. Other South American …

The cell surface of Trypanosoma brucei, like many protistan blood parasites, is crucial for
mediating host-parasite interactions and is instrumental to the initiation, maintenance and …

Oral transmission of Chagas disease has been documented in Latin American countries.
Nevertheless, significant studies on the pathophysiology of this form of infection are largely …

The evolution of parasitism is a recurrent event in the history of life and a core problem in
evolutionary biology. Trypanosomatids are important parasites and include the human …

African trypanosomes thrive in the bloodstream and tissue spaces of a wide range of
mammalian hosts. Infections of cattle cause an enormous socio-economic burden in sub …