Identification of EGFR expression status association with metastatic lymph node density (ND) by expression microarray analysis of advanced gastric cancer

A Ema, M Waraya, K Yamashita, K Kokubo… - Cancer …, 2015 - Wiley Online Library
Metastatic lymph node density (ND) has been reproducibly proven to be a prognostic factor
in gastric cancer. The molecular mechanisms that underlie this aggressiveness are …

[HTML][HTML] The H19-PEG10/IGF2BP3 axis promotes gastric cancer progression in patients with high lymph node ratios

S Ishii, K Yamashita, H Harada, H Ushiku, T Tanaka… - Oncotarget, 2017 - ncbi.nlm.nih.gov
We previously demonstrated that the lymph node ratio (LNR) is a prognostic factor
associated with EGFR expression, among first priority genes amplified or overexpressed in …

[HTML][HTML] An immunohistochemical study of EGFR expression in colorectal cancer and its correlation with lymph nodes status and tumor grade

M Mokhtari, MM Ardestani… - Journal of Research in …, 2012 - ncbi.nlm.nih.gov
Background: Colorectal cancer (CRC) is a common human malignancy. Epidermal growth
factor receptor (EGFR) is expressed in wide variety of human malignancies and is of some …

Lymph node ratio as a novel and simple prognostic factor in advanced gastric cancer

K Yamashita, K Hosoda, A Ema, M Watanabe - European Journal of …, 2016 - Elsevier
TNM staging is no doubt the most critical prognostic factors, representing tumor (T)/lymph
node metastasis (N)/distant metastasis (M) in gastric cancer. Lymph node ratio-based N …

Expression of EGFR, Her2 predict lymph node metastasis (LNM)-associated metastasis in colorectal cancer

Y Lu, G Jingyan, S Baorong, J Peng, Y Xu… - Cancer …, 2012 - content.iospress.com
Background: As key molecules that drive progression and chemoresistance in
gastrointestinal cancers, epidermal growth factor receptor (EGFR) and human epidermal …

[HTML][HTML] Epidermal growth factor receptor expression and gene copy number analysis in gastric carcinoma samples from Chinese patients

F Zhang, X Yang, L Li, L Sun… - Oncology …, 2016 - spandidos-publications.com
Epidermal growth factor receptor (EGFR) expression and gene copy number have been
observed to be associated with a positive clinical response to EGFR inhibitors. The present …

[HTML][HTML] Effect of epidermal growth factor receptor status on the outcomes of patients with metastatic gastric cancer: A pilot study

K Aydin, SK Okutur, M Bozkurt… - Oncology …, 2014 - spandidos-publications.com
The expression of epidermal growth factor receptor (EGFR) has been linked to clinical
outcome in several solid tumors. However, the clinical significance of EGFR (c‑erbB1) in …

Knockdown of EGFR inhibits growth and invasion of gastric cancer cells

Y Zhen, L Guanghui, Z Xiefu - Cancer gene therapy, 2014 - nature.com
The epidermal growth factor receptor (EGFR) is an oncogenic trans-membranous receptor,
which is overexpressed in multiple human cancers. However, the role of EGFR in gastric …

Epidermal growth factor receptor (EGFR) expression is associated with a worse prognosis in gastric cancer patients undergoing curative surgery

G Galizia, E Lieto, M Orditura… - World journal of …, 2007 - Wiley Online Library
Background In gastric cancer, the recurrence rate is high even after curative surgery. A
relevant issue is the identification of independent prognostic factors to select high‐risk …

High epidermal growth factor receptor expression in metastatic colorectal cancer lymph nodes may be more prognostic of poor survival than in primary tumor

Y Deng, BF Kurland, J Wang, J Bi, W Li… - American Journal of …, 2009 - journals.lww.com
Objectives: High epidermal growth factor receptor (EGFR) expression in the primary tumor
predicts poor survival in colorectal cancer. However, EGFR expression may be discordant in …