Statistical analysis of microarray time course data

YC Tai, TP Speed - DNA Microarrays, 2007 - taylorfrancis.com
This chapter discusses the statistical analysis of microarray time course data, with a focus on
developmental time course experiments. The methods reviewed here are generally suitable …

Molecular and statistical tools for circadian transcript profiling

H Wijnen, F Naef, MW Young - Methods in enzymology, 2005 - Elsevier
This article describes methods used to evaluate mRNA expression patterns on microarrays
and their application in circadian biology. With the intention of complementing rather than …

Identifying periodically expressed transcripts in microarray time series data

S Wichert, K Fokianos, K Strimmer - Bioinformatics, 2004 - academic.oup.com
Motivation: Microarray experiments are now routinely used to collect large-scale time series
data, for example to monitor gene expression during the cell cycle. Statistical analysis of this …

Microarrays: statistical methods for circadian rhythms

R Yamada, HR Ueda - Circadian Rhythms: Methods and Protocols, 2007 - Springer
Microarrays are promising tools that are increasingly being applied to the study of circadian
rhythms. The large and complex datasets they generate, however, mean they require a new …

Discovering statistically significant periodic gene expression

J Chen, KC Chang - International Statistical Review, 2008 - Wiley Online Library
One frequent application of microarray experiments is in the study of monitoring gene
activities in a cell during cell cycle or cell division. High throughput gene expression time …

A permutation-based multiple testing method for time-course microarray experiments

I Sohn, K Owzar, SL George, S Kim, SH Jung - BMC bioinformatics, 2009 - Springer
Background Time-course microarray experiments are widely used to study the temporal
profiles of gene expression. Storey et al.(2005) developed a method for analyzing time …

Identifying significant temporal variation in time course microarray data without replicates

SC Billups, MC Neville, M Rudolph, W Porter… - BMC …, 2009 - Springer
Background An important component of time course microarray studies is the identification
of genes that demonstrate significant time-dependent variation in their expression levels …

Microarray time course experiments: Finding profiles

I Irigoien, S Vives, C Arenas - IEEE/ACM Transactions on …, 2009 - ieeexplore.ieee.org
Time course studies with microarray techniques and experimental replicates are very useful
in biomedical research. We present, in replicate experiments, an alternative approach to …

Statistical analysis of gene expression studies with ordered experimental conditions

SD Peddada, DM Umbach, S Harris - Handbook of statistics, 2012 - Elsevier
In the past decade, the availability of microarray technology for monitoring the expression of
thousands of genes simultaneously has enhanced the ability of scientists to probe …

A unified mixed effects model for gene set analysis of time course microarray experiments

L Wang, X Chen, RD Wolfinger, JL Franklin… - … in genetics and …, 2009 - degruyter.com
Methods for gene set analysis test for coordinated changes of a group of genes involved in
the same biological process or molecular pathway. Higher statistical power is gained for …