Effects of antihypertensive treatment in one–clip, two kidney hypertension in rats. In order to
investigate the consequences of antihypertensive therapy on hormonal and renal …

Earlier experiments have shown that in sodium depleted hypertensive rats with bilaterally
constricted renal arteries the arterial pressure normalized after blockade of the renin …

Effects of chronic treatment with angiotensin converting enzyme inhibitor or an angiotensin
receptor antagonist in two-kidney, one-clip hypertensive rats. The effects of chronic …

1. Two-kidney one-clip hypertension was produced in rats by application of a 0.20 mm clip to
the left renal artery. 2. After three weeks, the animals had mildly elevated PRA, kidney renin …

Calcium blockade versus ACE inhibition in clipped and unclipped kidneys of 2K-1C rats.
ACE inhibitors have been shown to worsen the kidney damage occurring distal to a renal …

1. Blood pressure, renin concentration and angiotensin II were measured in
unanaesthetized two-kidney one-clip hypertensive rats at 1 and 2 days, at weekly intervals …

1. The effect of removal of the clip on blood pressure, plasma renin activity and the excretion
of water, sodium and potassium was studied in renal hypertensive rats. Hypertension was …

The intrarenal renin-angiotensin system (RAS) has an important role in generating and
maintaining hypertension in two-kidney, one-clip (2K1C) rats. This study evaluated how …

Recent studies with normal rats indicated that systemic administration of the angiotensin II
(AngII) type 1 (AT1) receptor blocker candesartan elicited divergent renal hemodynamic and …

The two-kidney, one clip (2K1C) model of hypertension in the rat does not uniformly result in
increased blood pressure. That is, the placement of a clip around one renal artery in a two …