Retinal processing near absolute threshold: from behavior to mechanism

GD Field, AP Sampath, F Rieke - Annu. Rev. Physiol., 2005 - annualreviews.org
▪ Abstract Vision at absolute threshold is based on signals produced in a tiny fraction of the
rod photoreceptors. This requires that the rods signal the absorption of single photons, and …

Behavioural and physiological limits to vision in mammals

GD Field, AP Sampath - Philosophical Transactions of …, 2017 - royalsocietypublishing.org
Human vision is exquisitely sensitive—a dark-adapted observer is capable of reliably
detecting the absorption of a few quanta of light. Such sensitivity requires that the sensory …

[HTML][HTML] Coincidence detection of single-photon responses in the inner retina at the sensitivity limit of vision

P Ala-Laurila, F Rieke - Current Biology, 2014 - cell.com
Background Vision in starlight relies on our ability to detect single absorbed photons.
Indeed, the sensitivity of dark-adapted vision approaches limits set by the quantal nature of …

Controlling the gain of rod-mediated signals in the mammalian retina

FA Dunn, T Doan, AP Sampath… - Journal of Neuroscience, 2006 - Soc Neuroscience
Effective sensory processing requires matching the gain of neural responses to the range of
signals encountered. For rod vision, gain controls operate at light levels at which photons …

Detection sensitivity and temporal resolution of visual signals near absolute threshold in the salamander retina

EJ Chichilnisky, F Rieke - Journal of Neuroscience, 2005 - Soc Neuroscience
Several studies have suggested that the visual system can detect dim lights with a fidelity
limited only by Poisson fluctuations in photon absorption and spontaneous activation of …

Visual threshold is set by linear and nonlinear mechanisms in the retina that mitigate noise: How neural circuits in the retina improve the signal‐to‐noise ratio of the …

J Pahlberg, AP Sampath - Bioessays, 2011 - Wiley Online Library
In sensory biology, a major outstanding question is how sensory receptor cells minimize
noise while maximizing signal to set the detection threshold. This optimization could be …

Transmission of single photon signals through a binary synapse in the mammalian retina

A Berntson, RG Smith, WR Taylor - Visual neuroscience, 2004 - cambridge.org
At very low light levels the sensitivity of the visual system is determined by the efficiency with
which single photons are captured, and the resulting signal transmitted from the rod …

Optimal processing of photoreceptor signals is required to maximize behavioural sensitivity

H Okawa, KJ Miyagishima, AC Arman… - The Journal of …, 2010 - Wiley Online Library
The sensitivity of receptor cells places a fundamental limit upon the sensitivity of sensory
systems. For example, the signal‐to‐noise ratio of sensory receptors has been suggested to …

[HTML][HTML] Single-photon absorptions evoke synaptic depression in the retina to extend the operational range of rod vision

FA Dunn, F Rieke - Neuron, 2008 - cell.com
Adaptation or gain control allows sensory neurons to encode diverse stimuli using a limited
range of output signals. Rod vision exemplifies a general challenge facing adaptational …

Photoreceptive retinal ganglion cells control the information rate of the optic nerve

N Milosavljevic, R Storchi… - Proceedings of the …, 2018 - National Acad Sciences
Information transfer in the brain relies upon energetically expensive spiking activity of
neurons. Rates of information flow should therefore be carefully optimized, but mechanisms …