Environmental assessment of Norwegian priority pharmaceuticals based on the EMEA guideline

M Grung, T Källqvist, S Sakshaug, S Skurtveit… - Ecotoxicology and …, 2008 - Elsevier
An environmental risk assessment of eleven pharmaceuticals according to the guideline
recommended by the European Medicines Evaluation Agency (EMEA) was performed …

Environmental risk assessment of human pharmaceuticals in Denmark after normal therapeutic use

F Stuer-Lauridsen, M Birkved, LP Hansen… - Chemosphere, 2000 - Elsevier
An environmental risk assessment is presented for the 25 most used pharmaceuticals in the
primary health sector in Denmark. Predicted environmental concentrations (PECs) for the …

Environmental risk assessment of six human pharmaceuticals: are the current environmental risk assessment procedures sufficient for the protection of the aquatic …

B Ferrari, R Mons, B Vollat, B Fraysse… - … and Chemistry: An …, 2004 - Wiley Online Library
In this study, exposure and ecotoxicity data of six human pharmaceuticals (carbamazepine,
clofibric acid, diclofenac, ofloxacin, propranolol, and sulfamethoxazole) were collected …

Environmental risk assessment for new human pharmaceuticals in the European Union according to the draft guideline/discussion paper of January 2001

JO Straub - Toxicology letters, 2002 - Elsevier
Since 1993, an environmental risk assessment (ERA) for a new drug application has been
stipulated by EU Directive 93/39/EEC amending Directive 65/65/EEC. In early 2001, after …

Evaluation of the accuracy and consistency of the Swedish Environmental Classification and Information System for pharmaceuticals

M Ågerstrand, C Rudén - Science of the Total Environment, 2010 - Elsevier
The Swedish environmental and classification system for pharmaceuticals is a voluntary,
industry-owned system with the purpose to provide environmental information about active …

Environmental risk assessment of medicinal products for human use according to European Commission recommendations

G Huschek, PD Hansen, HH Maurer… - Environmental …, 2004 - Wiley Online Library
Presented here, based on new recommendations of the European Commission, is an
environmental risk assessment (ERA) of a selected group of pharmaceuticals for Phase I …

Environmental hazard assessment of pharmaceuticals

KP Henschel, A Wenzel, M Diedrich… - Regulatory toxicology and …, 1997 - Elsevier
The pharmaceuticals and pharmaceutical metabolites salicylic acid, paracetamol, clofibrinic
acid, and methotrexate were examined with regard to their biological degradability and …

Use of acute and chronic ecotoxicity data in environmental risk assessment of pharmaceuticals

J Vestel, DJ Caldwell, L Constantine… - Environmental …, 2016 - Wiley Online Library
For many older pharmaceuticals, chronic aquatic toxicity data are limited. To assess risk
during development, scale‐up, and manufacturing processes, acute data and …

Improving environmental risk assessment of human pharmaceuticals

M Ågerstrand, C Berg, B Björlenius… - Environmental …, 2015 - ACS Publications
This paper presents 10 recommendations for improving the European Medicines Agency's
guidance for environmental risk assessment of human pharmaceutical products. The …

Environmental risk assessment of antibiotics in the Swedish environment with emphasis on sewage treatment plants

RH Lindberg, K Björklund, P Rendahl, MI Johansson… - Water research, 2007 - Elsevier
The potential risks associated with antibiotics present in the Swedish environment were
assessed using concentrations found in hospital effluent, and sewage treatment waters and …