Current state of the art MRI for the longitudinal assessment of cystic fibrosis

JC Woods, JM Wild, MO Wielpütz… - Journal of Magnetic …, 2020 - Wiley Online Library
Pulmonary MRI can now provide high‐resolution images that are sensitive to early disease
and specific to inflammation in cystic fibrosis (CF) lung disease. With specificity and function …

[HTML][HTML] The clinical use of lung MRI in cystic fibrosis: what, now, how?

G Dournes, LL Walkup, I Benlala, MM Willmering… - Chest, 2021 - Elsevier
To assess airway and lung parenchymal damage non-invasively in cystic fibrosis (CF), chest
MRI has been historically out of the scope of routine clinical imaging due to technical …

Lung function imaging methods in cystic fibrosis pulmonary disease

M Kołodziej, MJ de Veer, M Cholewa, GF Egan… - Respiratory …, 2017 - Springer
Monitoring of pulmonary physiology is fundamental to the clinical management of patients
with Cystic Fibrosis. The current standard clinical practise uses spirometry to assess lung …

Magnetic resonance imaging detects changes in structure and perfusion, and response to therapy in early cystic fibrosis lung disease

MO Wielpütz, M Puderbach… - American journal of …, 2014 - atsjournals.org
Rationale: Studies demonstrating early structural lung damage in infants and preschool
children with cystic fibrosis (CF) suggest that noninvasive monitoring will be important to …

Magnetic resonance imaging of the lung in cystic fibrosis

TA Altes, M Eichinger, M Puderbach - Proceedings of the American …, 2007 - atsjournals.org
Magnetic resonance imaging (MRI) can provide regional information about lung structural
changes in cystic fibrosis (CF), albeit at lower spatial and temporal resolution than computed …

Magnetic resonance imaging of cystic fibrosis lung disease

MO Wielpütz, M Eichinger… - Journal of thoracic …, 2013 - journals.lww.com
Lung involvement in cystic fibrosis (CF) disease continues to be a major life-limiting factor of
this autosomal recessive genetic disorder. Efforts made toward early diagnosis and …

[HTML][HTML] Hyperpolarized 129Xe for investigation of mild cystic fibrosis lung disease in pediatric patients

RP Thomen, LL Walkup, DJ Roach, ZI Cleveland… - Journal of Cystic …, 2017 - Elsevier
Background Cystic fibrosis (CF) is a genetic disease which carries high morbidity and
mortality from lung-function decline. Monitoring disease progression and treatment response …

Hyperpolarized HHe 3 MRI of the lung in cystic fibrosis: assessment at baseline and after bronchodilator and airway clearance treatment1

K Mentore, DK Froh, EE de Lange, JR Brookeman… - Academic radiology, 2005 - Elsevier
RATIONALE AND OBJECTIVES: The purpose of this study is to determine hyperpolarized
helium 3 (HHe) magnetic resonance (MR) findings of the lung in patients with cystic fibrosis …

Hyperpolarized gas magnetic resonance imaging of pediatric cystic fibrosis lung disease

G Santyr, N Kanhere, F Morgado, JH Rayment… - Academic radiology, 2019 - Elsevier
Conventional pulmonary function tests appear normal in early cystic fibrosis (CF) lung
disease. Therefore, new diagnostic approaches are required that can detect CF lung …

Quantitative evaluation of hyperpolarized helium-3 magnetic resonance imaging of lung function variability in cystic fibrosis

M Kirby, S Svenningsen, H Ahmed, A Wheatley… - Academic radiology, 2011 - Elsevier
Rationale and Objectives To better understand imaging measurement precision and
reproducibility and to provide guidance for measurements in individual cystic fibrosis (CF) …