[HTML][HTML] Bromelain inhibits the ability of colorectal cancer cells to proliferate via activation of ROS production and autophagy
TC Chang, PL Wei, PT Makondi, WT Chen, CY Huang… - PloS one, 2019 - journals.plos.org
Advanced colorectal cancer (CRC) survival rates are still low despite advances in cytotoxic
and targeted therapies. The development of new effective or alternative therapies is …
and targeted therapies. The development of new effective or alternative therapies is …
The chemopreventive action of bromelain, from pineapple stem (Ananas comosus L.), on colon carcinogenesis is related to antiproliferative and proapoptotic effects
Scope Colorectal cancer is an important health problem across the world. Here, we
investigated the possible antiproliferative/proapoptotic effects of bromelain (from the …
investigated the possible antiproliferative/proapoptotic effects of bromelain (from the …
Cytotoxic effects of bromelain in human gastrointestinal carcinoma cell lines (MKN45, KATO-III, HT29-5F12, and HT29-5M21)
A Amini, A Ehteda, S Masoumi Moghaddam… - OncoTargets and …, 2013 - Taylor & Francis
Background Bromelain is a pineapple stem extract with a variety of therapeutic benefits
arising from interaction with a number of different biological processes. Several preclinical …
arising from interaction with a number of different biological processes. Several preclinical …
[HTML][HTML] Salidroside induces apoptosis and autophagy in human colorectal cancer cells through inhibition of PI3K/Akt/mTOR pathway
XJ Fan, Y Wang, L Wang, M Zhu - Oncology Reports, 2016 - spandidos-publications.com
The role of salidroside in colon cancer remains unknown. Here we show that salidroside, a
phenylpropanoid glycoside extracted from Rhodiola rosea, exhibited potent anti-proliferative …
phenylpropanoid glycoside extracted from Rhodiola rosea, exhibited potent anti-proliferative …
[HTML][HTML] Bromelain and N-acetylcysteine inhibit proliferation and survival of gastrointestinal cancer cells in vitro: significance of combination therapy
A Amini, S Masoumi-Moghaddam, A Ehteda… - Journal of Experimental …, 2014 - Springer
Background Bromelain and N-acetylcysteine are two natural, sulfhydryl-containing
compounds with good safety profiles which have been investigated for their benefits and …
compounds with good safety profiles which have been investigated for their benefits and …
Bromelain's activity and potential as an anti-cancer agent: current evidence and perspectives
K Chobotova, AB Vernallis, FAA Majid - Cancer letters, 2010 - Elsevier
The medicinal qualities of pineapple are recognized in many traditions in South America,
China and Southeast Asia. These qualities are attributed to bromelain, a 95%-mixture of …
China and Southeast Asia. These qualities are attributed to bromelain, a 95%-mixture of …
[HTML][HTML] Berberine induces caspase-independent cell death in colon tumor cells through activation of apoptosis-inducing factor
L Wang, L Liu, Y Shi, H Cao, R Chaturvedi, MW Calcutt… - PloS one, 2012 - journals.plos.org
Berberine, an isoquinoline alkaloid derived from plants, is a traditional medicine for treating
bacterial diarrhea and intestinal parasite infections. Although berberine has recently been …
bacterial diarrhea and intestinal parasite infections. Although berberine has recently been …
Targeting of oncogenic signaling pathways by berberine for treatment of colorectal cancer
J Hallajzadeh, P Maleki Dana, M Mobini, Z Asemi… - Medical oncology, 2020 - Springer
Studies indicate that inhibiting a single signaling pathway or one single product of a gene is
insufficient for the prevention and treatment of cancer. This is due to the fact that …
insufficient for the prevention and treatment of cancer. This is due to the fact that …
Bufalin induces autophagy-mediated cell death in human colon cancer cells through reactive oxygen species generation and JNK activation
CM Xie, WY Chan, S Yu, J Zhao, CHK Cheng - Free Radical Biology and …, 2011 - Elsevier
Colorectal cancer is the second most common cause of cancer death in the world and about
half of the patients with colorectal cancer require adjuvant therapy after surgical resection …
half of the patients with colorectal cancer require adjuvant therapy after surgical resection …
Nimbolide, a limonoid triterpene, inhibits growth of human colorectal cancer xenografts by suppressing the proinflammatory microenvironment
Purpose: Extensive research over the past decade has revealed that the proinflammatory
microenvironment plays a critical role in the development of colorectal cancer. Whether …
microenvironment plays a critical role in the development of colorectal cancer. Whether …