Sensory over-responsivity is related to GABAergic inhibition in thalamocortical circuits

ET Wood, KK Cummings, J Jung, G Patterson… - Translational …, 2021 - nature.com
Abstract Sensory over-responsivity (SOR), extreme sensitivity to or avoidance of sensory
stimuli (eg, scratchy fabrics, loud sounds), is a highly prevalent and impairing feature of …

Reduced modulation of thalamocortical connectivity during exposure to sensory stimuli in ASD

SA Green, L Hernandez, SY Bookheimer… - Autism …, 2017 - Wiley Online Library
Recent evidence for abnormal thalamic connectivity in autism spectrum disorders (ASD) and
sensory processing disorders suggests the thalamus may play a role in sensory over …

Distinct patterns of neural habituation and generalization in children and adolescents with autism with low and high sensory overresponsivity

SA Green, L Hernandez, KE Lawrence… - American Journal of …, 2019 - Am Psychiatric Assoc
Objective: Sensory overresponsivity (SOR), an atypical negative reaction to sensory stimuli,
is highly prevalent in autism spectrum disorder (ASD). Previous work has related SOR to …

Neurobiology of sensory overresponsivity in youth with autism spectrum disorders

SA Green, L Hernandez, N Tottenham… - JAMA …, 2015 - jamanetwork.com
Importance More than half of youth with autism spectrum disorders (ASDs) have sensory
overresponsivity (SOR), an extreme negative reaction to sensory stimuli. However, little is …

Increased resting‐state thalamocortical functional connectivity in children and young adults with autism spectrum disorder

B Baran, QTH Nguyen, D Mylonas… - Autism …, 2023 - Wiley Online Library
There is converging evidence that abnormal thalamocortical interactions contribute to
attention deficits and sensory sensitivities in autism spectrum disorder (ASD). However …

Overreactive brain responses to sensory stimuli in youth with autism spectrum disorders

SA Green, JD Rudie, NL Colich, JJ Wood… - Journal of the American …, 2013 - Elsevier
Objectives Sensory over-responsivity (SOR), defined as a negative response to or
avoidance of sensory stimuli, is both highly prevalent and extremely impairing in youth with …

Associations between physiological and neural measures of sensory reactivity in youth with autism

J Jung, TD Zbozinek, KK Cummings… - Journal of Child …, 2021 - Wiley Online Library
Background Individuals with Autism Spectrum Disorder (ASD) commonly show sensory over‐
responsivity (SOR), an impairing condition related to over‐reactive brain and behavioral …

Region-specific elevations of glutamate+ glutamine correlate with the sensory symptoms of autism spectrum disorders

JL He, G Oeltzschner, M Mikkelsen, A Deronda… - Translational …, 2021 - nature.com
Individuals on the autism spectrum are often reported as being hyper-and/or hyporeactive to
sensory input. These sensory symptoms were one of the key observations that led to the …

Associations between thalamocortical functional connectivity and sensory over-responsivity in infants at high likelihood for ASD

L Wagner, M Banchik, NJ Okada, N McDonald… - Cerebral …, 2023 - academic.oup.com
Despite growing evidence implicating thalamic functional connectivity atypicalities in autism
spectrum disorder (ASD), it remains unclear how such alterations emerge early in human …

[HTML][HTML] GABA concentration in the left ventral premotor cortex associates with sensory hyper-responsiveness in autism spectrum disorders without intellectual …

Y Umesawa, T Atsumi, M Chakrabarty… - Frontiers in …, 2020 - frontiersin.org
Individuals with autism spectrum disorder (ASD) often exhibit abnormal processing of
sensory inputs from multiple modalities and higher-order cognitive/behavioral response to …