Aberrant G‐protein coupled receptor expression in relation to adrenocortical overfunction

A Lacroix, I Bourdeau, A Lampron… - Clinical …, 2010 - Wiley Online Library
The aberrant adrenal expression and function of one or several G‐protein coupled receptors
can lead to cell proliferation and abnormal regulation of steroidogenesis in unilateral …

Aberrant G-protein coupled hormone receptor in adrenal diseases

M St-Jean, N El Ghorayeb, I Bourdeau… - Best Practice & Research …, 2018 - Elsevier
The regulation of cortisol or aldosterone production when ACTH of pituitary origin or the
renin-angiotensin systems are suppressed in primary adrenal Cushing's syndrome or in …

Multiple aberrant hormone receptors in Cushing's syndrome

N El Ghorayeb, I Bourdeau… - European Journal of …, 2015 - academic.oup.com
The mechanisms regulating cortisol production when ACTH of pituitary origin is suppressed
in primary adrenal causes of Cushing's syndrome (CS) include diverse genetic and …

Aberrant expression of hormone receptors in adrenal Cushing's syndrome

S Christopoulos, I Bourdeau, A Lacroix - Pituitary, 2004 - Springer
In recent years, a novel understanding of the pathophysiology of adrenal Cushing's
syndrome has emerged. The ectopic or aberrant expression of G-protein-coupled hormone …

Food-dependent Cushing's syndrome: from molecular characterization to therapeutical results

NM Albiger, G Occhi, B Mariniello… - European Journal of …, 2007 - academic.oup.com
Objective Cortisol secretion in ACTH-independent macronodular adrenal hyperplasia
(AIMAH) may be regulated by the aberrant expression of several G-protein-coupled …

Molecular basis of primary aldosteronism and adrenal Cushing syndrome

P Vaduva, F Bonnet, J Bertherat - Journal of the Endocrine …, 2020 - academic.oup.com
This review reports the main molecular alterations leading to development of benign cortisol-
and/or aldosterone-secreting adrenal tumors. Causes of adrenal Cushing syndrome can be …

Ectopic and abnormal hormone receptors in adrenal Cushing's syndrome

A Lacroix, NN′ Diaye, J Tremblay… - Endocrine …, 2001 - academic.oup.com
The mechanism by which cortisol is produced in adrenal Cushing's syndrome, when ACTH
is suppressed, was previously unknown and was referred to as being “autonomous.” More …

Systematic analysis of G protein-coupled receptor gene expression in adrenocorticotropin-independent macronodular adrenocortical hyperplasia identifies novel …

G Assie, E Louiset, N Sturm… - The Journal of …, 2010 - academic.oup.com
Context: Stimulation of cortisol secretion through abnormally expressed G protein-coupled
receptors (GPCRs) is a frequent feature of ACTH-independent macronodular adrenal …

Are ectopic or abnormal membrane hormone receptors frequently present in adrenal Cushing's syndrome?

H Mircescu, J Jilwan, NN′ Diaye… - The Journal of …, 2000 - academic.oup.com
Twenty consecutive patients with adrenal Cushing's syndrome were studied with an in vivo
protocol to determine the prevalence and diversity of the presence of ectopic or abnormal …

Clinical and genetic heterogeneity, overlap with other tumor syndromes, and atypical glucocorticoid hormone secretion in adrenocorticotropin-independent …

HP Hsiao, LS Kirschner, I Bourdeau… - The Journal of …, 2009 - academic.oup.com
Objective: ACTH-independent macronodular adrenal hyperplasia (AIMAH) is often
associated with subclinical cortisol secretion or atypical Cushing's syndrome (CS). We …