Immunoglobulins, or antibodies, are monospecific, bivalent antigen-binding molecules.
Bifunctional antibodies are bispecific, with each arm binding to a different antigen, and may …

Bispecific antibodies are immunoglobulin molecules with two different antigen binding sites.
They can be prepared either by chemical crosslinking of immunoglobulins with different …

The binding of at least two molecular targets simultaneously with a single bispecific antibody
is an attractive concept. The use of bispecific antibodies as possible therapeutic agents for …

Monoclonal Antibodies (Mabs) represent a promising tool for cancer diagnosis and
theraphy. Administration of MAbs alone or conjugated to cytotoxic agents has been …

Antibodies with two distinet binding specificities have great potential for a wide range of
clinical applications as targeting agents for in vitro and in vivo immunodiagnosis and …

Bispecific antibodies are artificially engineered monoclonal antibodies (MAbs) that consist of
two distinct binding sites and are capable of binding two different antigens noncovalently …

Bispecific antibodies have immense potential as reagents and in medicine. Until recently,
they were made by combining monoclonal antibodies of two different specificities in vitro, or …

This book provides a comprehensive overview of antibody technology. It discusses in detail
the new generation of engineered antibodies and the latest developments in immunoassay …

Several laboratories have now shown that monoclonal antibodies having enzyme-like
properties can be generated. The generation of catalytic antibodies makes use of the same …

The emergence of novel binding proteins or antibody mimetics capable of binding to ligand
analytes in a manner analogous to that of the antigen–antibody interaction has spurred …