Optogenetic techniques have been developed to allow control over the activity of selected
cells within a highly heterogeneous tissue, using a combination of genetic engineering and …

Light is fundamental to life on earth. Therefore, nature has evolved a multitude of
photoreceptors that sense light across all kingdoms. This natural resource provides synthetic …

Optogenetics: controlling cell function with light | Nature Methods Skip to main content Thank
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Highlights•Optogenetics uses light to control genetically encoded cell components.•It is a
precise tool for systematically addressing complex biological questions.•It has a potential for …

Optogenetics is an innovative technique for optical control of cells. This field has exploded
over the past decade or so and has given rise to great advances in neuroscience. A variety …

The ability to remote control the expression of therapeutic genes in mammalian cells in order
to treat disease is a central goal of synthetic biology‐inspired therapeutic strategies …

Genetically encoded, single-component optogenetic tools have made a significant impact on
neuroscience, enabling specific modulation of selected cells within complex neural tissues …

Optogenetics is a rapidly evolving field of technology that allows optical control of genetically
targeted biological systems at high temporal and spatial resolution. By heterologous …

In complex multicellular systems, such as the brain or the heart, the ability to selectively
perturb and observe the response of individual components at the cellular level and with …

The ability to manipulate expression of exogenous genes in particular regions of living
organisms has profoundly transformed the way we study biomolecular processes involved in …