Peripheral artery disease (PAD) poses a great challenge to society, with a growing
prevalence in the upcoming years. Patients in the severe stages of PAD are prone to …

Peripheral arterial disease (PAD) is a major health care problem. There have been limited
advances in medical therapies, and a huge burden of symptomatic patients with intermittent …

Therapeutic angiogenesis utilizing genetic and cellular modalities in the treatment of arterial
obstructive diseases continues to evolve. This is, in part, because the mechanism of …

The World Health Organization announced that cardiovascular disease is the number one
cause of death globally, representing 31% of all global deaths. Coronary artery disease …

Gene therapy and cell‐based therapy have emerged as novel therapies to promote
therapeutic angiogenesis in critical limb ischemia (CLI) caused by peripheral artery disease …

Critical limb ischemia (CLI) is a severe form of peripheral artery disease associated with
high morbidity and mortality. The primary therapeutic goals in treating CLI are to reduce the …

BACKGROUND: We reviewed the issue of stem cells and therapeutic angiogenesis in the
treatment of peripheral vascular disease using METHODS: MEDLINE (1997–2008) with the …

The prevalence of peripheral arterial disease (PAD) in the United States exceeds 10 million
people, and PAD is a significant cause of morbidity and mortality across the globe. PAD is …

Recently, with the better understanding of the mechanisms of neovascularization, many new
therapeutic approaches to enhance neovascularization have emerged. Of these diverse …

Therapeutic angiogenesis for peripheral artery disease (PAD), achieved by gene and cell
therapy, has recently raised a great deal of hope for patients who cannot undergo standard …