In the central nervous system (CNS), dopamine is involved in the control of locomotion,
cognition, affect and neuroendocrine secretion. These actions of dopamine are mediated by …

DZ doyan~ ine receptor ncfiuntion indltces i~ &ibition ofndenylate cyclnse, zuifll n rapid
decrease of CAMP levels, and nri ensuing blockade of IPj-dependent release of Cc++ from …

Dopamine is a major neurotransmitter in the central nervous system. Receptors for this
catecholamine are of considerable interest, as they are the principal target of drugs …

Recent progress in understanding the molecular biology and pharmacology of dopamine
receptors in mammalian brain has been remarkable and can serve as a basis for …

The D3 dopamine receptor, a D2-like receptor, is selectively expressed in the ventral
striatum, particularly in the shell of nucleus accumbens and islands of Calleja, where it is …

A polyclonal antibody was generated using synthetic peptides designed in a specific
sequence of the rat D3 receptor (D3R). Using transfected cells expressing recombinant …

The dopamine D2 receptor belongs to the family of seven transmembrane domain G-protein-
coupled receptors and is highly expressed in the central nervous system and the pituitary …

The dopamine D2 and D3 receptors are members of the D2 subfamily that includes the D2,
D3 and D4 receptor. In the rat, the D3 receptor exhibits a distribution restricted to mesolimbic …

The recent impact of new drugs acting selectively on Dl dopamine receptors is reviewed. l-
phenyl-lH-3-benzazepines, typified by SCH 23390, SK&F 83566 and SK&F 38393 …

The D 3 dopamine receptor is a member of the family of D 2-like dopamine receptors. Since
the cloning and identification of the D 3 receptor in 1990, considerable progress has been …