BACKGROUND Proliferative inflammatory atrophy (PIA) in the prostate has been proposed
to be a precursor to prostate cancer. CCAAT/enhancer‐binding protein beta (C/EBPβ) is an …

Abstract BACKGROUND C/EBPβ is a transcription factor regulating key biological processes
including cellular growth and differentiation and its increased expression correlates with …

Background Chronic inflammation has been suggested to be linked to the development and
progression of prostate cancer. An inflammatory microenvironment may support the …

The proliferative inflammatory atrophy (PIA) is considered as a possible precursor of
prostate intraepithelial neoplasia (PIN) or prostate cancer (PCa). In this study we assessed …

INTRODUCTION The complexity of acute and chronic inflammatory processes may either
lead to benign prostate hyperplasia (BPH) and/or prostate cancer. Obviously, various tissue …

BACKGROUND Inflammation has been implicated as a potential etiological agent in human
prostate cancer (PCa). Proliferative inflammatory atrophy (PIA) in prostate consists of areas …

Background C/EBPα is a critical mediator of terminal differentiation and a tumor suppressor
through its strong antiproliferative actions on cell cycle regulatory proteins. C/EBPα also …

Proliferative inflammatory atrophy (PIA) belongs to the atrophic lesions that frequently occur
in the prostate. The location of PIA in the periphery of the gland near to prostate carcinoma …

BACKGROUND CCAAT/enhancer‐binding protein β (C/EBPβ) is a transcription factor and
consists of three isoforms, transcription‐activating A/B (C/EBPβ‐AB) and transcription …

Abstract BACKGROUND The CCAAT/Enhancer binding protein alpha (C/EBPα) is an
important transcription factor for granulopoiesis and adipogenesis. While decreased …