In vitro assembly of virus-like particles and their applications
Virus-like particles (VLPs) are increasingly used for vaccine development and drug delivery.
Assembly of VLPs from purified monomers in a chemically defined reaction is advantageous …
Assembly of VLPs from purified monomers in a chemically defined reaction is advantageous …
[PDF][PDF] Advances and challenges in enveloped virus-like particle (VLP)-based vaccines
S Dai, H Wang, F Deng - Journal of …, 2018 - immunologyresearchjournal.com
Virus-like particles (VLPs) are highly organized particles that self-assemble from viral
structural proteins. Like parental viruses, VLPs can be either non-enveloped or enveloped …
structural proteins. Like parental viruses, VLPs can be either non-enveloped or enveloped …
Bioengineering virus‐like particles as vaccines
LHL Lua, NK Connors, F Sainsbury… - Biotechnology and …, 2014 - Wiley Online Library
Virus‐like particle (VLP) technology seeks to harness the optimally tuned immunostimulatory
properties of natural viruses while omitting the infectious trait. VLPs that assemble from a …
properties of natural viruses while omitting the infectious trait. VLPs that assemble from a …
Engineering virus-like particles for antigen and drug delivery
Virus-like particles (VLPs) are nanoscale biological structures consisting of viral proteins
assembled in a morphology that mimic the native virion but do not contain the viral genetic …
assembled in a morphology that mimic the native virion but do not contain the viral genetic …
Virus-like particles: flexible platforms for vaccine development
B Chackerian - Expert review of vaccines, 2007 - Taylor & Francis
Virus-like particles (VLPs) consist of viral structural proteins that, when overexpressed,
spontaneously self-assemble into particles that are antigenically indistinguishable from …
spontaneously self-assemble into particles that are antigenically indistinguishable from …
Towards the preparative and large-scale precision manufacture of virus-like particles
LK Pattenden, APJ Middelberg, M Niebert… - Trends in …, 2005 - cell.com
Virus-like particles (VLPs) are of interest in vaccination, gene therapy and drug delivery, but
their potential has yet to be fully realized. This is because existing laboratory processes …
their potential has yet to be fully realized. This is because existing laboratory processes …
[PDF][PDF] Virus-like particles as drug delivery vectors
M Zdanowicz, J Chroboczek - Acta Biochimica Polonica, 2016 - bibliotekanauki.pl
Virus-like particles (VLPs) assemble spontaneously during the viral cycle or in heterologous
systems during expression of viral structural protein. Depending on the complexity of the …
systems during expression of viral structural protein. Depending on the complexity of the …
The application of virus-like particles as vaccines and biological vehicles
D Yan, YQ Wei, HC Guo, SQ Sun - Applied microbiology and …, 2015 - Springer
Virus-like particles (VLPs) can be spontaneously self-assembled by viral structural proteins
under appropriate conditions in vitro while excluding the genetic material and potential …
under appropriate conditions in vitro while excluding the genetic material and potential …
The role of virus-like particles in medical biotechnology
M Comas-Garcia, M Colunga-Saucedo… - Molecular …, 2020 - ACS Publications
Virus-like particles (VLPs) are protein-based, nanoscale, self-assembling, cage
architectures, which have relevant applications in biomedicine. They can be used for the …
architectures, which have relevant applications in biomedicine. They can be used for the …
Virus-like particles: the future of microbial factories and cell-free systems as platforms for vaccine development
Highlights▶ Microorganisms are inexpensive platforms to produce chimeric VLPs.▶
Bacteriophage-derived VLPs are excellent structures for drug delivery.▶ Microbial cell …
Bacteriophage-derived VLPs are excellent structures for drug delivery.▶ Microbial cell …