Cisplatin-loaded graphene oxide/chitosan/hydroxyapatite composite as a promising tool for osteosarcoma-affected bone regeneration

M Sumathra, KK Sadasivuni, SS Kumar, M Rajan - Acs Omega, 2018 - ACS Publications
Presently, tissue engineering approaches have been focused toward finding new potential
scaffolds with osteoconductivity on bone-disease-affected cells. This work focused on the …

The synergistic effect of a hybrid graphene oxide–chitosan system and biomimetic mineralization on osteoblast functions

D Depan, TC Pesacreta, RDK Misra - Biomaterials Science, 2014 - pubs.rsc.org
Graphene oxide and chitosan are promising materials for tissue regeneration. The present
study explores a novel biomimetic mineralization route employing a graphene oxide (GO) …

Enhanced physiochemical and mechanical performance of chitosan‐grafted graphene oxide for superior Osteoinductivity

J Ruan, X Wang, Z Yu, Z Wang, Q Xie… - Advanced Functional …, 2016 - Wiley Online Library
The regeneration of artificial bone substitutes is a potential strategy for repairing bone
defects. However, the development of substitutes with appropriate osteoinductivity and …

A phosphorylated chitosan armed hydroxyapatite nanocomposite for advancing activity on osteoblast and osteosarcoma cells

M Sumathra, M Rajan, MA Munusamy - New Journal of Chemistry, 2018 - pubs.rsc.org
Recently, applications of traditional medicine in tissue engineering have gained increasing
attention. The components in ginger possess potent antioxidant and anti-inflammatory …

Preliminary in vitro evaluation of chitosan–graphene oxide scaffolds on osteoblastic adhesion, proliferation, and early differentiation

SHM Wong, SS Lim, TJ Tiong, PL Show… - International Journal of …, 2020 - mdpi.com
An ideal scaffold should be biocompatible, having appropriate microstructure, excellent
mechanical strength yet degrades. Chitosan exhibits most of these exceptional properties …

In situ synthesis and biocompatibility of nano hydroxyapatite on pristine and chitosan functionalized graphene oxide

M Li, Y Wang, Q Liu, Q Li, Y Cheng, Y Zheng… - Journal of Materials …, 2013 - pubs.rsc.org
Motivated by the success of using graphene oxide (GO) as a nanofiller of composites, there
is a drive to search for this new kind of carbon material as a reinforcing phase in …

In situ synthesis and cell line studies of nano-hydroxyapatite/graphene oxide composite materials for bone support applications

MN Ozder, F Çiftçi, O Rencuzogullari, ED Arisan… - Ceramics …, 2023 - Elsevier
The current work presents and discusses the findings of on the structural, chemical and
thermal properties of in situ synthesis of graphene oxide-hydroxyapatite (GO/HA) …

Enhanced bioactivity and osteoinductivity of carboxymethyl chitosan/nanohydroxyapatite/graphene oxide nanocomposites

Z Yu, C Xiao, Y Huang, M Chen, W Wei, X Yang… - RSC …, 2018 - pubs.rsc.org
Tissue engineering approaches combine a bioscaffold with stem cells to provide biological
substitutes that can repair bone defects and eventually improve tissue functions. The …

Biomimetic mineralized hierarchical graphene oxide/chitosan scaffolds with adsorbability for immobilization of nanoparticles for biomedical applications

C Xie, X Lu, L Han, J Xu, Z Wang, L Jiang… - … applied materials & …, 2016 - ACS Publications
Biomimetic calcium phosphate mineralized graphene oxide/chitosan (GO/CS) scaffolds with
hierarchical structures were developed. First, GO/CS scaffolds with large micropores (∼ 300 …

Development of new graphene oxide incorporated tricomponent scaffolds with polysaccharides and hydroxyapatite and study of their osteoconductivity on MG-63 cell …

R Rajesh, YD Ravichandran - RSC Advances, 2015 - pubs.rsc.org
Regenerative medicine witnessed a paradigm shift from synthetic implants and tissue grafts
to a tissue engineering approach that incorporates biodegradable, bioceramic composite …