Novel investigational treatments for ventilator-associated pneumonia and critically ill patients in the intensive care unit

R Cusack, A Garduno, K Elkholy… - Expert Opinion on …, 2022 - Taylor & Francis
Introduction Ventilator-associated pneumonia (VAP) is common; its prevalence has been
highlighted by the Covid-19 pandemic. Even young patients can suffer severe nosocomial …

Ventilator-associated pneumonia: the role of emerging diagnostic technologies

MH Kollef, CAD Burnham - Seminars in respiratory and critical …, 2017 - thieme-connect.com
Antibiotic resistance has emerged as a key determinant of outcome in patients with serious
infections along with the virulence of the underlying pathogen. Within the intensive care unit …

Tackling empirical antibiotic therapy for ventilator-associated pneumonia in your ICU: guidance for implementing the guidelines

JL Kuti, E Shore, M Palter… - Seminars in respiratory …, 2009 - thieme-connect.com
Guidelines published jointly by the American Thoracic Society and Infectious Diseases
Society of America endorse the practice of appropriate empirical antibiotic therapy for …

[HTML][HTML] Bench-to-bedside review: therapeutic options and issues in the management of ventilator-associated bacterial pneumonia

J Rello - Critical Care, 2004 - Springer
Despite progress in the diagnosis, prevention and therapy for hospital-acquired infections,
ventilator-associated pneumonia (VAP) continues to complicate the course of a significant …

[HTML][HTML] New treatments of multidrug-resistant Gram-negative ventilator-associated pneumonia

G Poulakou, S Lagou… - Annals of …, 2018 - ncbi.nlm.nih.gov
Ventilator-associated pneumonia (VAP) remains an important clinical problem globally,
being associated with significant morbidity and mortality. As management of VAP requires …

Optimizing Antibiotic Treatment for Ventilator‐Associated Pneumonia

ST Micek, TJ Heuring, JM Hollands… - … : The Journal of …, 2006 - Wiley Online Library
Ventilator‐associated pneumonia (VAP) is the most common infectious complication in
patients receiving mechanical ventilation and accounts for exorbitant use of resources in the …

New perspectives in the antibiotic treatment of mechanically ventilated patients with infections from Gram-negatives

M Karvouniaris, K Pontikis, T Nitsotolis… - Expert Review of Anti …, 2021 - Taylor & Francis
Introduction: Ventilator-associated pneumonia (VAP) is a common and potentially fatal
complication of mechanical ventilation that is often caused by multidrug-resistant (MDR) …

Challenges and opportunities in the treatment of ventilator-associated pneumonia

MP Schreiber, AF Shorr - Expert Review of Anti-Infective Therapy, 2017 - Taylor & Francis
Introduction: Ventilator-associated pneumonia (VAP) is a distinct clinical entity characterized
by an onset after 48 hours of the application of mechanical ventilation (MV). Protocols exist …

Nosocomial pneumonia in the ICU—year 2000 and beyond

DL Bowton - Chest, 1999 - Elsevier
Diagnostic and treatment strategies in ICU patients with ventilator-associated pneumonia
(VAP) remain controversial, largely because of the paucity of well-controlled comparison …

Should antibiotic combinations be used to treat ventilator-associated pneumonia?

P Eggimann, JP Revelly - Seminars in respiratory and critical …, 2006 - thieme-connect.com
This review summarizes the rationale for using or not using combinations of antibiotics to
treat ventilator-associated pneumonia (VAP). Patients suffering from VAP require empirical …