Landscape of mobile genetic elements and their antibiotic resistance cargo in prokaryotic genomes
Abstract Prokaryotic Mobile Genetic Elements (MGEs) such as transposons, integrons,
phages and plasmids, play important roles in prokaryotic evolution and in the dispersal of …
phages and plasmids, play important roles in prokaryotic evolution and in the dispersal of …
Mobile genetic elements: the agents of open source evolution
LS Frost, R Leplae, AO Summers… - Nature Reviews …, 2005 - nature.com
Horizontal genomics is a new field in prokaryotic biology that is focused on the analysis of
DNA sequences in prokaryotic chromosomes that seem to have originated from other …
DNA sequences in prokaryotic chromosomes that seem to have originated from other …
Strain-level characterization of broad host range mobile genetic elements transferring antibiotic resistance from the human microbiome
Mobile genetic elements (MGEs) carrying antibiotic resistance genes (ARGs) disseminate
ARGs when they mobilise into new bacterial hosts. The nature of such horizontal gene …
ARGs when they mobilise into new bacterial hosts. The nature of such horizontal gene …
[HTML][HTML] How do interactions between mobile genetic elements affect horizontal gene transfer?
T Horne, VT Orr, JPJ Hall - Current Opinion in Microbiology, 2023 - Elsevier
Highlights•Collaboration and conflict between MGEs can promote and inhibit HGT•Many
genome defences are MGE-encoded, serving MGE interests and changing frequently•The …
genome defences are MGE-encoded, serving MGE interests and changing frequently•The …
mobileOG-db: a manually curated database of protein families mediating the life cycle of bacterial mobile genetic elements
Bacterial mobile genetic elements (MGEs) encode functional modules that perform both core
and accessory functions for the element, the latter of which are often only transiently …
and accessory functions for the element, the latter of which are often only transiently …
A bioinformatic analysis of integrative mobile genetic elements highlights their role in bacterial adaptation
Mobile genetic elements (MGEs) contribute to bacterial adaptation and evolution; however,
high-throughput, unbiased MGE detection remains challenging. We describe MGEfinder, a …
high-throughput, unbiased MGE detection remains challenging. We describe MGEfinder, a …
Genetic dominance governs the evolution and spread of mobile genetic elements in bacteria
J Rodríguez-Beltrán, V Sørum… - Proceedings of the …, 2020 - National Acad Sciences
Mobile genetic elements (MGEs), such as plasmids, promote bacterial evolution through
horizontal gene transfer (HGT). However, the rules governing the repertoire of traits encoded …
horizontal gene transfer (HGT). However, the rules governing the repertoire of traits encoded …
Defense systems are pervasive across chromosomally integrated mobile genetic elements and are inversely correlated to virulence and antimicrobial resistance
J Botelho - Nucleic acids research, 2023 - academic.oup.com
Mobile genetic elements (MGEs) are key promoters of microbial evolution. These elements
can be located extrachromosomally or integrated into the chromosome. Well-known …
can be located extrachromosomally or integrated into the chromosome. Well-known …
Comprehensive analysis of chromosomal mobile genetic elements in the gut microbiome reveals phylum-level niche-adaptive gene pools
Mobile genetic elements (MGEs) drive extensive horizontal transfer in the gut microbiome.
This transfer could benefit human health by conferring new metabolic capabilities to …
This transfer could benefit human health by conferring new metabolic capabilities to …
Horizontal gene transfer and mobile genetic elements in marine systems
PA Sobecky, TH Hazen - Horizontal gene transfer: genomes in flux, 2009 - Springer
The pool of mobile genetic elements (MGE) in microbial communities consists of viruses,
plasmids, and associated elements (insertion sequences, transposons, and integrons) that …
plasmids, and associated elements (insertion sequences, transposons, and integrons) that …