Oleanolic acid is a pentacyclic triterpenoid compound that exists widely in medicinal herbs
and other plants. Because of the extensive pharmacological activity, oleanolic acid has …

Oleanolic acid (OA), a ubiquitous pentacyclic oleanane-type triterpene isolated from edible
and medicinal plants, exhibits a wide spectrum of pharmacological activities and …

The increasing demand for natural products as an alternative therapy for chronic diseases
has encouraged research into the pharmacological importance of bioactive compounds from …

Objective To summarize the pharmacological function of oleanolic acid. Method Based on
the documents and related achievements, the pharmacological function and its mechanism …

Introduction: Oleanolic acid belongs to the pentacyclic triterpene family. In China, oleanolic
acid has been used as an over the counter (OTC) hepatoprotective drug for decades …

A highly selective and sensitive HPLC–ESI–MS–MS method was developed for the
determination of oleanolic acid in human plasma. The oleanolic acid and glycyrrhetinic acid …

Oleanolic acid, a pentacyclic triterpenoid ubiquitously present in the plant kingdom, is
receiving outstanding attention from the scientific community due to its biological activity …

The pharmacokinetics of oleanolic acid was evaluated in vitro and in vivo. From Caco‐2 cell
permeation studies, oleanolic acid was a low permeability compound with no directional …

Oleanolic acid (OA) is a typical BCS IV drug with low water-solubility and poor permeability,
metabolized by cytochrome P450 (CYP) isozymes in the intestinal tract, such as CYP3A …

The natural product oleanolic acid has been widely used for treating hepatopathy in China,
whereas its clinical application was confined by poor solubility in water. Inspired by …