The cerebral ischemia injury can result in neuronal death and/or functional impairment,
which leads to further damage and dysfunction after recovery of blood supply. Cerebral …

Ischemic stroke is the second leading cause of death and disability worldwide and is
associated with significant clinical and socioeconomic implications, emphasizing the need …

It has been demonstrated by numerous studies that apoptotic cell death pathways are
implicated in ischemic cerebral injury in ischemia models in vivo. Experimental ischemia …

Acute ischemic stroke is the third leading cause of death in industrialized countries and the
most frequent cause of permanent disability in adults worldwide. Despite advances in the …

Oxidative/nitrosative stress and neuroinflammation are critical pathological processes in
cerebral ischemia-reperfusion injury, and their intimate interactions mediate neuronal …

The mechanisms leading to cellular damage from ischemia-reperfusion (I/R) injury are
complex and multi-factorial. Accumulating evidence suggests an important role for oxidative …

The pathogenesis of acute brain ischemia (ABI) is highly complex and involves multiple
mechanisms including free radical generation. Imbalance between the cellular production of …

Stroke is the second leading cause of global death and is characterized by high rates of
mortality and disability. Oxidative stress is accompanied by other pathological processes …

Its increasing incidence has led stroke to be the second leading cause of death worldwide.
Despite significant advances in recanalization strategies, patients are still at risk for …

Stroke is the second leading cause of death, after ischemic heart disease, and accounts for
9% of deaths worldwide. According to the World Health Organization [WHO], 15 million …