Osteoarthritis (OA) is a degenerative disease of the joints and is one of the leading causes of
disability in adults. However, there are no key therapeutics for OA and medical treatment is …

Osteoarthritis (OA) is the most common form of arthritis resulting in joint discomfort and
disability, culminating in decline in life quality. Attention has been drawn in recent years to …

OBJECTIVE: Osteoarthritis (OA) is the most common rheumatic pathology. It is related to
aging and is characterized primarily by cartilage degradation. Despite its high prevalence …

Osteoarthritis (OA) is a chronic degenerative joint disease. The pathogenesis is poorly
understood. What is known is that OA is characterized by imbalance in anabolic and …

Osteoarthritis (OA) is a disease of the whole joint organ, characterized by the loss of
cartilage, and structural changes in bone including the formation of osteophytes, causing …

CONTEXT: Molecules that are released into biological fluids during matrix metabolism of
articular cartilage, subchondral bone, and synovial tissue could serve as biochemical …

Objective The aim of this narrative review is to summarize important findings from
biochemical marker studies relevant to osteoarthritis (OA) in the context of new discoveries …

The current diagnosis of osteoarthritis (OA) relies on the description of pain symptoms,
affected joint stiffness, and radiography used as the reference technique for determining the …

Objective To summarize recent scientific advances in protein-derived soluble biomarkers of
osteoarthritis. Design A systematic search on the PubMed electronic database of clinical …

Biomarker combinations have the ability to subgroup the heterogenous osteoarthritis
population to allow a better scrutiny of diagnosis and treatment options. The application of …