Elevated fetal steroidogenic activity in autism
S Baron-Cohen, B Auyeung… - Molecular …, 2015 - nature.com
Autism affects males more than females, giving rise to the idea that the influence of steroid
hormones on early fetal brain development may be one important early biological risk factor …
hormones on early fetal brain development may be one important early biological risk factor …
Foetal oestrogens and autism
Elevated latent prenatal steroidogenic activity has been found in the amniotic fluid of autistic
boys, based on measuring prenatal androgens and other steroid hormones. To date, it is …
boys, based on measuring prenatal androgens and other steroid hormones. To date, it is …
Prenatal versus postnatal sex steroid hormone effects on autistic traits in children at 18 to 24 months of age
B Auyeung, J Ahluwalia, L Thomson, K Taylor… - Molecular autism, 2012 - Springer
Background Studies of prenatal exposure to sex steroid hormones predict autistic traits in
children at 18 to 24 and at 96 months of age. However, it is not known whether postnatal …
children at 18 to 24 and at 96 months of age. However, it is not known whether postnatal …
Polycystic ovary syndrome and autism: a test of the prenatal sex steroid theory
A Cherskov, A Pohl, C Allison, H Zhang… - Translational …, 2018 - nature.com
Elevated levels of prenatal testosterone may increase the risk for autism spectrum conditions
(autism). Given that polycystic ovary syndrome (PCOS) is also associated with elevated …
(autism). Given that polycystic ovary syndrome (PCOS) is also associated with elevated …
Perinatal testosterone exposure and autistic-like traits in the general population: a longitudinal pregnancy-cohort study
AJO Whitehouse, E Mattes, MT Maybery… - Journal of …, 2012 - Springer
Background Increased prenatal testosterone exposure has been hypothesized as a
mechanism underlying autism spectrum disorders (ASD). However, no studies have …
mechanism underlying autism spectrum disorders (ASD). However, no studies have …
Implications of prenatal steroid perturbations for neurodevelopment, behavior, and autism
The prenatal brain develops under the influence of an ever-changing hormonal milieu that
includes endogenous fetal gonadal and adrenal hormones, placental and maternal …
includes endogenous fetal gonadal and adrenal hormones, placental and maternal …
Marked elevation of adrenal steroids, especially androgens, in saliva of prepubertal autistic children
MD Majewska, M Hill, E Urbanowicz… - European child & …, 2014 - Springer
Autism is diagnosed on the basis of behavioral manifestations, but its biomarkers are not
well defined. A strong gender bias typifying autism (it is 4–5 times more prevalent in males) …
well defined. A strong gender bias typifying autism (it is 4–5 times more prevalent in males) …
Foetal testosterone and autistic traits in 18 to 24-month-old children
B Auyeung, K Taylor, G Hackett, S Baron-Cohen - Molecular autism, 2010 - Springer
Background Autism spectrum conditions have been characterised as an extreme
presentation of certain male-typical psychological traits. In addition, several studies have …
presentation of certain male-typical psychological traits. In addition, several studies have …
Increased serum androstenedione in adults with autism spectrum conditions
L Ruta, E Ingudomnukul, K Taylor, B Chakrabarti… - …, 2011 - Elsevier
Molecular and behavioural evidence points to an association between sex-steroid
hormones and autism spectrum conditions (ASC) and/or autistic traits. Prenatal androgen …
hormones and autism spectrum conditions (ASC) and/or autistic traits. Prenatal androgen …
Gene expression profiling of lymphoblasts from autistic and nonaffected sib pairs: altered pathways in neuronal development and steroid biosynthesis
VW Hu, AT Nguyen, KS Kim, ME Steinberg… - PloS one, 2009 - journals.plos.org
Despite the identification of numerous autism susceptibility genes, the pathobiology of
autism remains unknown. The present “case-control” study takes a global approach to …
autism remains unknown. The present “case-control” study takes a global approach to …