[HTML][HTML] Effectiveness of decontamination protocols when analyzing ancient DNA preserved in dental calculus

AG Farrer, SL Wright, E Skelly, R Eisenhofer… - Scientific reports, 2021 - nature.com
Ancient DNA analysis of human oral microbial communities within calcified dental plaque
(calculus) has revealed key insights into human health, paleodemography, and cultural …

[HTML][HTML] Differential preservation of endogenous human and microbial DNA in dental calculus and dentin

AE Mann, S Sabin, K Ziesemer, ÅJ Vågene… - Scientific reports, 2018 - nature.com
Dental calculus (calcified dental plaque) is prevalent in archaeological skeletal collections
and is a rich source of oral microbiome and host-derived ancient biomolecules. Recently, it …

Ancient DNA analysis of dental calculus

LS Weyrich, K Dobney, A Cooper - Journal of Human Evolution, 2015 - Elsevier
Dental calculus (calcified tartar or plaque) is today widespread on modern human teeth
around the world. A combination of soft starchy foods, changing acidity of the oral …

The sustainability of dental calculus for archaeological research

M Mackie, A Radini, CF Speller - Shallow Pasts, Endless Horiozons …, 2017 - pure.york.ac.uk
Dental calculus is a mineralized plaque biofilm formed by microbiota of the oral microbiome.
Until recently, the vast research potential of dental calculus for archaeological study was not …

[PDF][PDF] Interbreeding between Neanderthals and modern humans: Remarks and methodological dangers of a dental calculus microbiome analysis

P Charlier, F Gaultier, G Héry-Arnaud - J. Hum. Evol, 2019 - academia.edu
Since at least the 1980s, it has been known that archaeological dental calculus contains
preserved cellular structures of oral bacteria, but it was only recently discovered that it is also …

[HTML][HTML] A unified protocol for simultaneous extraction of DNA and proteins from archaeological dental calculus

Z Fagernäs, MI García-Collado, J Hendy… - Journal of …, 2020 - Elsevier
Archaeological materials are a finite resource, and efforts should be made to minimize
destructive analyses. This can be achieved by using protocols combining extraction of …

[HTML][HTML] Tracing back ancient oral microbiomes and oral pathogens using dental pulps from ancient teeth

N Rascovan, H Huynh, G Chouin, K Adekola… - npj Biofilms and …, 2016 - nature.com
Ancient dental pulps are highly precious samples because they conserve DNA from humans
and blood-borne pathogens for ages. However, little is known about the microbial …

[HTML][HTML] Oral health status in historic population: Macroscopic and metagenomic evidence

C Willmann, X Mata, K Hanghoej, L Tonasso… - PLoS …, 2018 - journals.plos.org
Recent developments in High-Throughput DNA sequencing (HTS) technologies and ancient
DNA (aDNA) research have opened access to the characterization of the microbial …

Reducing microbial and human contamination in DNA extractions from ancient bones and teeth

P Korlević, T Gerber, MT Gansauge, M Hajdinjak… - …, 2015 - Taylor & Francis
Although great progress has been made in improving methods for generating DNA
sequences from ancient biological samples, many, if not most, samples are still not …

[HTML][HTML] Do I have something in my teeth? The trouble with genetic analyses of diet from archaeological dental calculus

AE Mann, JAF Yates, Z Fagernäs, RM Austin… - Quaternary …, 2023 - Elsevier
Dental calculus and other preserved microbiome substrates are an attractive target for
dietary reconstruction in past populations through a variety of physical, chemical, and …