The development of all humans begins after the union of male and female gametes or germ
cells during fertilization or conception. The fertilized egg or zygote is a large diploid cell that …

Research of stem cells has caught much attention in the past few years with its promise for
therapeutic and regenerative applications in a variety of diseases and organ systems. The …

Disruption of the lung architecture by genetic events, environmental insults, or
transformation can lead to respiratory diseases such as acute respiratory distress syndrome …

The lung has vital functions in gas exchange and immune defense. To fulfill these functions
the cellular composition and complex three‐dimensional organization of the organ must be …

Ex ovo omnia (William Harvey, circa 1620) The future is in eggs (Eugene Ionesco, circa
1960) Recently, the National Heart, Lung and Blood Institute (NHLBI) sponsored a …

The epithelial cells lining the mammalian lung are subjected to constant interaction with the
external environment, necessitating robust regeneration strategies to deal with cell loss due …

At the cornerstone of contemporary biology are investigations on mechanisms of repair,
remodeling, proliferation, and differentiation after injury in complex tissue such as lung …

The current enthusiasm for stem cell research stems from the hope that damaged or
diseased tissues may one day be repaired through the manipulation of endogenous or …

[Frontiers in Bioscience 12, 3117-3124, May 1, 2007] 3117 Advancing the field of lung stem
cell biology Carla Bender Kim Stem Ce Page 1 [Frontiers in Bioscience 12, 3117-3124, May 1 …

The ability to replace defective cells in an airway with cells that can engraft, integrate, and
restore a functional epithelium could potentially cure a number of lung diseases. Progress …