Aberrant O-glycans expressed at the surface of cancer cells consist of membrane-tethered
glycoproteins (T and Tn antigens) and glycolipids (Lewis a, Lewis x and Forssman …

The scientific description of lectins, a class of sugar‐binding proteins distinct from both sugar‐
specific enzymes and antibodies, began nearly 100 years ago. The natural ligands of lectins …

Cancer remains a global health challenge, with high morbidity and mortality, despite the
recent advances in diagnosis and treatment. Multiple compounds assessed as novel …

Tn antigen (α-O-GalNAc-Ser/Thr) is a convenient cancer biomarker that is recognized by
antibodies and lectins. This work yields remarkable results for two plant lectins in terms of …

Simple Summary Changes in glycosylation, such as incomplete synthesis and higher
density of O-glycans on the cell surface, are frequently observed in cancer cells. Several …

Since the early discovery of plant lectins at the end of the 19th century, and the finding that
they could agglutinate erythrocytes and precipitate glycans from their solutions, many …

Growing insights into the many roles of glycoconjugates in biorecognition as ligands for
lectins indicates a need to compare plant and animal lectins. Furthermore, the popularity of …

Social behavior of cells depends on membrane glycosylation, including cell communication,
adhesion and migration. Malignant transformation is associated with alterations in cell …

Oligosaccharides can store biological information. In this respect, their capacity even
outmatches that of oligo-and polymeric structures of nucleotides and amino acids. Protein …

Plant lectins are non-immunoglobin in nature and bind to the carbohydrate moiety of the
glycoconjugates without altering any of the recognized glycosyl ligands. Plant lectins have …