Sarsasapogenin, a principal active component absorbed into blood of total saponins of Anemarrhena, attenuates proliferation and invasion in rheumatoid arthritis …
Y Dai, P Liu, W Wen, P Li, C Yang… - Phytotherapy …, 2023 - Wiley Online Library
Increased glycolytic in fibroblast‐like synoviocytes (FLS) of rheumatoid arthritis (RA) not only
contributes to early‐stage disease pathogenesis but leads to sustained proliferation of FLS …
contributes to early‐stage disease pathogenesis but leads to sustained proliferation of FLS …
N6-methyladenosine modification of TGM2 mRNA contributes to the inhibitory activity of sarsasapogenin in rheumatoid arthritis fibroblast-like synoviocytes
X Lin, C Tao, R Zhang, M Zhang, Q Wang, J Chen - Phytomedicine, 2022 - Elsevier
Background Developing alternative targets and drugs for rheumatoid arthritis (RA) treatment
is currently an urgent issue. The relationship between TGM2 and the abnormal immune …
is currently an urgent issue. The relationship between TGM2 and the abnormal immune …
Anti-rheumatoid arthritic effects of Paris Saponin VII in human rheumatoid arthritis fibroblast-like Synoviocytes and adjuvant-induced arthritis in rats
M Meng, Z Yue, L Chang, Y Liu, J Hu, Z Song… - Frontiers in …, 2021 - frontiersin.org
In the pathogenesis of rheumatoid arthritis (RA), rheumatoid arthritis fibroblast-like
synoviocytes (RA-FLS) have tumor-like characteristics, mainly manifested by …
synoviocytes (RA-FLS) have tumor-like characteristics, mainly manifested by …
[HTML][HTML] The antiangiogenic effect of total saponins of Panax japonicus CA Meyer in rheumatoid arthritis is mediated by targeting the HIF-1α/VEGF/ANG-1 axis
X Guo, J Zhang, Z Feng, J Ji, X Shen, X Hou… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance Traditional Chinese herbal medicine Panax
japonicus CA Meyer has a long history in clinical treatment of rheumatoid arthritis (RA). Total …
japonicus CA Meyer has a long history in clinical treatment of rheumatoid arthritis (RA). Total …
Triterpene saponins from Guo-gang-long attenuate collagen-induced arthritis via regulating A20 and inhibiting MAPK pathway
H Xiong, M Luo, Y Ju, Z Zhao, M Zhang, R Xu… - Journal of …, 2021 - Elsevier
Ethnopharmacological relevance The stems of Entada phaseoloides (L.) Merr commonly
named “Guo-gang-long”, is a traditional Chinese folk medicine that has been used clinically …
named “Guo-gang-long”, is a traditional Chinese folk medicine that has been used clinically …
Ethanolic extract of Kaempferia parviflora interrupts the mechanisms-associated rheumatoid arthritis in SW982 culture model via p38/STAT1 and STAT3 pathways
P Kongdang, R Jaitham, S Thonghoi, C Kuensaen… - Phytomedicine, 2019 - Elsevier
Abstract Background Kaempferia parviflora Wall. ex Baker (KP) has long been used in
traditional medicine to treat various diseases because active compounds in rhizome extracts …
traditional medicine to treat various diseases because active compounds in rhizome extracts …
Total Saponin from Anemone flaccida Fr. Schmidt Prevents Bone Destruction in Experimental Rheumatoid Arthritis via Inhibiting Osteoclastogenesis
C Liu, Y Yang, D Sun, C Wang, H Wang, S Jia… - Rejuvenation …, 2015 - liebertpub.com
Abstract Anemone flaccida Fr. Schmidt is used in the clinical compound prescription for the
treatment of rheumatoid arthritis (RA) in China and has the traditional use of draining …
treatment of rheumatoid arthritis (RA) in China and has the traditional use of draining …
Transcriptomic profiling revealed the role of apigenin-4′-O-α-L-rhamnoside in inhibiting the activation of rheumatoid arthritis fibroblast-like synoviocytes via MAPK …
D Cao, Q Fan, Z Li, M Chen, Y Jiang, R Lin, J Li… - Phytomedicine, 2022 - Elsevier
Background Activated fibroblast-like synoviocyte (FLS) played a significant role in the
pathogenesis and progression of rheumatoid arthritis (RA). Apigenin-4′-O-α-L-rhamnoside …
pathogenesis and progression of rheumatoid arthritis (RA). Apigenin-4′-O-α-L-rhamnoside …
Anti-inflammation effects of the total saponin fraction from Dioscorea nipponica Makino on rats with gouty arthritis by influencing MAPK signalling pathway
Q Zhou, HJ Sun, SM Liu, XH Jiang, QY Wang… - … medicine and therapies, 2020 - Springer
Abstract Background Dioscorea nipponica Makino is widely used in traditional Chinese
medicine to treat gouty arthritis. Methods Sixty male Wistar rats were divided into six groups …
medicine to treat gouty arthritis. Methods Sixty male Wistar rats were divided into six groups …
The suppressive effects of Saposhnikovia divaricata (Fangfeng) chromone extract on rheumatoid arthritis via inhibition of nuclear factor-κB and mitogen activated …
X Kong, C Liu, C Zhang, J Zhao, J Wang, H Wan… - Journal of …, 2013 - Elsevier
Ethnopharmacological relevance Saposhnikovia divaricata (SD), called “Fangfeng” in
China, is commonly used in clinical compound prescription for treatment of rheumatoid …
China, is commonly used in clinical compound prescription for treatment of rheumatoid …
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