Streptococcus pneumoniae asymptomatically colonizes the upper respiratory tract of
children and is a frequent cause of otitis media. Patterns of microbial colonization likely …

The composition of the upper respiratory tract microbial community may influence the risk for
colonization by the acute otitis media (AOM) pathogens Streptococcus pneumoniae …

Objective The aim of this study was to profile and compare the middle ear microbiomes of
human subjects with and without chronic otitis media. Study Design Prospective multicenter …

Background Interferences between pathogenic bacteria and specific commensals are
known. We determined the interactions between nasopharyngeal microbial pathogens and …

Background. Interspecies interactions of the nasopharyngeal microbiota are likely to be
involved in the pathogenesis of acute otitis media (AOM). Capturing the breadth of microbial …

The microbiota of the upper respiratory tract (URT) protects the host from bacterial
pathogenic colonization by competing for adherence to epithelial cells and by immune …

Background Otitis media (OM) imposes a great burden of disease in indigenous populations
around the world, despite a variety of treatment and prevention programs. Improved …

Background The nasopharynx is a reservoir for pathogens associated with respiratory
illnesses such as asthma. Next-generation sequencing (NGS) has been used to …

Chronic otitis media with effusion (OME) has been associated with a shift in microbiome
composition and microbial interaction in the upper respiratory tract (URT). While most …

Background Recurrent acute otitis media (rAOM, recurrent ear infection) is a common
childhood disease caused by bacteria termed otopathogens, for which current treatments …