Previous data indicate a role of IL-1 and IL-1RA imbalance in bladder carcinoma (BC); the
inhibition of IL-1 signaling might be considered a treatment option. Objective: To assess …

Results We found that IL-1α was highly expressed in BCa patients while highly expressed IL-
1α was significantly related to short overall survival and progression-free survival in BCa as …

Background: The interleukin-1-receptor antagonist IL1RA (encoded by the IL1RN gene) is a
potent competitive antagonist to interleukin-1 (IL1) and thereby is mainly involved in the …

Objective: To investigate whether the previously reported association between IL-1α mRNA
levels and survival in urinary bladder cancer remains in an extended patient material and to …

We used gene expression profiling to identify inflammatory cytokines that correlate with
bladder cancer development. Gene expression profiles of the tissue samples were …

Background Urothelial carcinoma (UC) is one of most common genitourinary malignancy
and the spectrum of disease ranges from in situ lesions to muscle-invasive cancers. The non …

Urothelial cancer patients are prone to recurrence, and there is no marker to predict which
cases become refractory to the immunotherapy given to these patients. Tumour behaviour is …

Introduction: IL4I1, also known as Interleukin-4-induced gene 1, is an enzyme that can
modulate the immune system by acting as a L-amino acid oxidase. Nevertheless, a precise …

Bladder Cancer (BC) is a common disease worldwide. Chronic inflammation is one of the
key mechanisms for the development of BC. This study enrolled 40 patients. Preoperative …

Abstract Purpose: Interleukin (IL)-8 is an important mediator of angiogenesis, tumorigenicity,
and metastasis in transitional cell carcinoma (TCC) of the bladder. Nuclear factor κB (NF …