Numerous acquired hemostatic abnormalities have been identified in renal insufficiency.
Hemodialysis procedures add to these disturbances as they repetitively imply turbulent …

Appropriate anticoagulation for hemodialysis (HD) requires a subtle balance between under‐
and over‐heparinization to prevent extracorporeal circuit (ECC) clotting and bleeding …

The coagulation cascade is complex but well studied. Dialysis membranes and lines are
inherently pro‐coagulant and activate both the intrinsic and extrinsic pathways of …

In patients on chronic dialysis, unfractionated heparin (UFH) is the most commonly used
agent for anticoagulation of the hemodialysis extracorporeal circuit, for hemodialysis …

Background. A single bolus of dalteparin at the start of haemodialysis (HD) may prevent clot
formation, but subclinical activation of platelets and coagulation may still occur …

For patients undergoing dialysis with a high risk of haemorrhage there is no standardized
procedure for anticoagulation during extra-corporeal circulation. Minimal heparinization with …

Heparin-induced thrombocytopenia (HIT) is characterized by thrombocytopenia and
paradoxical hypercoagulability. HIT occurs when an antibody (“HIT antibody”) produced …

The effect of oral anticoagulation on clotting during hemodialysis. Background Between 5%
and 10% of hemodialysis patients are treated with oral anticoagulants. It is currently …

BACKGROUND: Hemodialysis requires anticoagulation to prevent clotting of the
extracorporeal circuit. Systemic anticoagulation with heparin is contraindicated in patients at …

Continuous renal replacement therapies are increasingly used to treat acute renal failure
(ARF) in the intensive care unit setting. The slow and steady removal of plasma water and/or …